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6O0D
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BU of 6o0d by Molmil
Saxiphilin Apo structure
Descriptor: Saxiphilin
Authors:Yen, T.J, Lolicato, M, Minor, D.L.
Deposit date:2019-02-16
Release date:2019-07-10
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the saxiphilin:saxitoxin (STX) complex reveals a convergent molecular recognition strategy for paralytic toxins.
Sci Adv, 5, 2019
6O2V
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BU of 6o2v by Molmil
Crystal structure of the SARAF luminal domain Cys-lock mutant monomer
Descriptor: FORMIC ACID, GLYCEROL, Store-operated calcium entry-associated regulatory factor
Authors:Kimberlin, C.R, Minor, D.L.
Deposit date:2019-02-24
Release date:2019-05-29
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:SARAF Luminal Domain Structure Reveals a Novel Domain-Swapped beta-Sandwich Fold Important for SOCE Modulation.
J.Mol.Biol., 431, 2019
7PG8
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BU of 7pg8 by Molmil
NaV_Ae1/Sp1CTD_pore-ANT05 complex
Descriptor: ANT05 H12 fab fragment, heavy chain, light chain, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGF
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BU of 7pgf by Molmil
Calcium-selective Sp1 channel pore domain only
Descriptor: Ion transporter
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGG
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BU of 7pgg by Molmil
NaVAb1p detergent (DM)
Descriptor: 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, Ion transport protein
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-15
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
6BGJ
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BU of 6bgj by Molmil
Cryo-EM structure of the TMEM16A calcium-activated chloride channel in LMNG
Descriptor: Anoctamin-1, CALCIUM ION
Authors:Dang, S, Feng, S, Tien, J, Peters, C.J, Bulkley, D, Lolicato, M, Zhao, J, Zuberbuhler, K, Ye, W, Qi, L, Chen, T, Craik, C.S, Jan, Y.N, Minor Jr, D.L, Cheng, Y, Jan, L.Y.
Deposit date:2017-10-28
Release date:2017-12-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures of the TMEM16A calcium-activated chloride channel.
Nature, 552, 2017
6BGI
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BU of 6bgi by Molmil
Cryo-EM structure of the TMEM16A calcium-activated chloride channel in nanodisc
Descriptor: Anoctamin-1, CALCIUM ION
Authors:Dang, S, Feng, S, Tien, J, Peters, C.J, Bulkley, D, Lolicato, M, Zhao, J, Zuberbuhler, K, Ye, W, Qi, J, Chen, T, Craik, C.S, Jan, Y.N, Minor Jr, D.L, Cheng, Y, Jan, L.Y.
Deposit date:2017-10-28
Release date:2017-12-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures of the TMEM16A calcium-activated chloride channel.
Nature, 552, 2017
6V37
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BU of 6v37 by Molmil
K2P2.1(TREK-1)I110D:RuR:ML335 bound channel structure
Descriptor: CADMIUM ION, DODECANE, HEXANE, ...
Authors:Pope, L, Lolicato, M, Minor, D.L.
Deposit date:2019-11-25
Release date:2020-02-26
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism.
Cell Chem Biol, 2020
6V3I
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BU of 6v3i by Molmil
K2P2.1(TREK-1)I110D:RuR bound channel structure
Descriptor: CADMIUM ION, DODECANE, HEXANE, ...
Authors:Pope, L, Lolicato, M, Minor, D.L.
Deposit date:2019-11-25
Release date:2020-02-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism.
Cell Chem Biol, 2020
6V36
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BU of 6v36 by Molmil
K2P2.1(TREK-1)I110D apo channel structure
Descriptor: CADMIUM ION, N-OCTANE, POTASSIUM ION, ...
Authors:Pope, L, Lolicato, M, Minor, D.L.
Deposit date:2019-11-25
Release date:2020-02-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism.
Cell Chem Biol, 2020
6W7B
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BU of 6w7b by Molmil
K2P2.1 (TREK-1), 0 mM K+
Descriptor: CADMIUM ION, DECANE, DODECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-19
Release date:2021-01-27
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.88 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W84
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BU of 6w84 by Molmil
K2P2.1 (TREK-1), 200 mM K+
Descriptor: CADMIUM ION, DODECANE, N-OCTANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W8A
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BU of 6w8a by Molmil
K2P2.1 (TREK-1):ML335 complex, 10 mM K+
Descriptor: CADMIUM ION, DODECANE, HEXADECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W8F
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BU of 6w8f by Molmil
K2P2.1 (TREK-1):ML335 complex, 0 mM K+
Descriptor: CADMIUM ION, DODECANE, HEXADECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W7D
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BU of 6w7d by Molmil
K2P2.1 (TREK-1), 10 mM K+
Descriptor: CADMIUM ION, DODECANE, HEXADECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-19
Release date:2021-01-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6V3C
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BU of 6v3c by Molmil
K2P2.1(TREK-1)I110D:Ru360 bound channel structure
Descriptor: CADMIUM ION, HEXANE, N-OCTANE, ...
Authors:Pope, L, Lolicato, M, Minor, D.L.
Deposit date:2019-11-25
Release date:2020-02-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism.
Cell Chem Biol, 2020
6W82
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BU of 6w82 by Molmil
K2P2.1 (TREK-1), 50 mM K+
Descriptor: CADMIUM ION, DECANE, DODECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W86
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BU of 6w86 by Molmil
K2P2.1 (TREK-1):ML335 complex, 100 mM K+
Descriptor: CADMIUM ION, DECANE, DODECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.299 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W7E
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BU of 6w7e by Molmil
K2P2.1 (TREK-1), 30 mM K+
Descriptor: CADMIUM ION, DODECANE, HEXADECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-19
Release date:2021-01-27
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W83
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BU of 6w83 by Molmil
K2P2.1 (TREK-1), 100 mM K+
Descriptor: CADMIUM ION, DECANE, DODECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.901 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W87
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BU of 6w87 by Molmil
K2P2.1 (TREK-1):ML335 complex, 50 mM K+
Descriptor: CADMIUM ION, DECANE, DODECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W88
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BU of 6w88 by Molmil
K2P2.1 (TREK-1):ML335 complex, 30 mM K+
Descriptor: CADMIUM ION, DECANE, DODECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W85
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BU of 6w85 by Molmil
K2P2.1 (TREK-1):ML335 complex, 200 mM K+
Descriptor: CADMIUM ION, DECANE, HEXADECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
6W8C
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BU of 6w8c by Molmil
K2P2.1 (TREK-1):ML335 complex, 1 mM K+
Descriptor: CADMIUM ION, DODECANE, HEXADECANE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2020-03-20
Release date:2021-01-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
7PGB
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BU of 7pgb by Molmil
NaV_Ae1/Sp1CTD_pore-SAT09 complex
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-NITROBENZOIC ACID, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022

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