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4CLU
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BU of 4clu by Molmil
Crystal structure of human soluble Adenylyl Cyclase with pyrophosphate
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ADENYLATE CYCLASE TYPE 10, ...
Authors:Kleinboelting, S, Weyand, M, Steegborn, C.
Deposit date:2014-01-15
Release date:2014-03-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111, 2014
3R5G
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BU of 3r5g by Molmil
Crystal structure of the adenylyl cyclase CyaB from P. aeruginosa
Descriptor: CyaB, GLYCEROL
Authors:Topal, H, Steegborn, C.
Deposit date:2011-03-18
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure and Regulation Mechanisms of the CyaB Adenylyl Cyclase from the Human Pathogen Pseudomonas aeruginosa.
J.Mol.Biol., 416, 2012
5IV4
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BU of 5iv4 by Molmil
Crystal structure of the human soluble adenylyl cyclase in complex with the allosteric inhibitor LRE1
Descriptor: 1,2-ETHANEDIOL, 6-chloro-N~4~-cyclopropyl-N~4~-[(thiophen-2-yl)methyl]pyrimidine-2,4-diamine, ACETATE ION, ...
Authors:Kleinboelting, S, Steegborn, C.
Deposit date:2016-03-18
Release date:2016-08-17
Last modified:2022-11-30
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.
Nat.Chem.Biol., 12, 2016
5IV3
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BU of 5iv3 by Molmil
Crystal structure of human soluble adenylyl cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate and the allosteric inhibitor LRE1
Descriptor: 1,2-ETHANEDIOL, 6-chloro-N~4~-cyclopropyl-N~4~-[(thiophen-2-yl)methyl]pyrimidine-2,4-diamine, ACETATE ION, ...
Authors:Kleinboelting, S, Steegborn, C.
Deposit date:2016-03-18
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.
Nat.Chem.Biol., 12, 2016
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