4DL3
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![BU of 4dl3 by Molmil](/molmil-images/mine/4dl3) | Human DNA polymerase eta inserting dCMPNPP opposite GG template (GG0b). | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*TP*AP*CP*GP*GP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*AP*C)-3'), ... | Authors: | Zhao, Y, Biertumpfel, C, Gregory, M, Hua, Y, Hanaoka, F, Yang, W. | Deposit date: | 2012-02-05 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta Proc.Natl.Acad.Sci.USA, 109, 2012
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4DL5
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![BU of 4dl5 by Molmil](/molmil-images/mine/4dl5) | Human DNA polymerase eta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2). | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DNA (5'-D(*TP*AP*CP*GP*GP*TP*CP*AP*CP*AP*CP*T)-3'), ... | Authors: | Zhao, Y, Biertumpfel, C, Gregory, M, Hanaoka, F, Hua, Y, Yang, W. | Deposit date: | 2012-02-05 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta Proc.Natl.Acad.Sci.USA, 109, 2012
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4DL7
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![BU of 4dl7 by Molmil](/molmil-images/mine/4dl7) | Human DNA polymerase eta fails to extend primer 2 nucleotide after cisplatin crosslink (Pt-GG4). | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*TP*AP*CP*TP*CP*GP*GP*TP*CP*AP*CP*T)-3'), ... | Authors: | Zhao, Y, Biertumpfel, C, Gregory, M, Hua, Y, Hanaoka, F, Yang, W. | Deposit date: | 2012-02-05 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta Proc.Natl.Acad.Sci.USA, 109, 2012
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1UB4
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![BU of 1ub4 by Molmil](/molmil-images/mine/1ub4) | |
1V33
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![BU of 1v33 by Molmil](/molmil-images/mine/1v33) | Crystal structure of DNA primase from Pyrococcus horikoshii | Descriptor: | DNA primase small subunit, PHOSPHATE ION, ZINC ION | Authors: | Ito, N, Nureki, O, Shirouzu, M, Yokoyama, S, Hanaoka, F, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-10-25 | Release date: | 2004-03-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis. Genes Cells, 8, 2003
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1V34
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![BU of 1v34 by Molmil](/molmil-images/mine/1v34) | Crystal structure of Pyrococcus horikoshii DNA primase-UTP complex | Descriptor: | DNA primase small subunit, URIDINE 5'-TRIPHOSPHATE, ZINC ION | Authors: | Ito, N, Nureki, O, Shirouzu, M, Yokoyama, S, Hanaoka, F, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-10-25 | Release date: | 2004-03-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis. Genes Cells, 8, 2003
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2FZL
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![BU of 2fzl by Molmil](/molmil-images/mine/2fzl) | |
2FWR
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![BU of 2fwr by Molmil](/molmil-images/mine/2fwr) | Structure of Archaeoglobus Fulgidis XPB | Descriptor: | DNA repair protein RAD25, ISOPROPYL ALCOHOL, PHOSPHATE ION | Authors: | Fan, L, Arvai, A.S, Tainer, J.A. | Deposit date: | 2006-02-02 | Release date: | 2006-04-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Conserved XPB Core Structure and Motifs for DNA Unwinding: Implications for Pathway Selection of Transcription or Excision Repair Mol.Cell, 22, 2006
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2FZ4
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![BU of 2fz4 by Molmil](/molmil-images/mine/2fz4) | |
1UEL
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![BU of 1uel by Molmil](/molmil-images/mine/1uel) | Solution structure of ubiquitin-like domain of hHR23B complexed with ubiquitin-interacting motif of proteasome subunit S5a | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4, UV excision repair protein RAD23 homolog B | Authors: | Fujiwara, K, Tenno, T, Jee, J.G, Sugasawa, K, Ohki, I, Kojima, C, Tochio, H, Hiroaki, H, Hanaoka, H, Shirakawa, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-05-19 | Release date: | 2004-02-10 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure of the Ubiquitin-interacting Motif of S5a Bound to the Ubiquitin-like Domain of HR23B J.Biol.Chem., 279, 2004
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4A11
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![BU of 4a11 by Molmil](/molmil-images/mine/4a11) | Structure of the hsDDB1-hsCSA complex | Descriptor: | DNA DAMAGE-BINDING PROTEIN 1, DNA EXCISION REPAIR PROTEIN ERCC-8 | Authors: | Bohm, K, Scrima, A, Fischer, E.S, Gut, H, Thomae, N.H. | Deposit date: | 2011-09-13 | Release date: | 2011-12-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
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4A0K
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![BU of 4a0k by Molmil](/molmil-images/mine/4a0k) | STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX | Descriptor: | 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ... | Authors: | Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H. | Deposit date: | 2011-09-09 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (5.93 Å) | Cite: | The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
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4A0L
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![BU of 4a0l by Molmil](/molmil-images/mine/4a0l) | Structure of DDB1-DDB2-CUL4B-RBX1 bound to a 12 bp abasic site containing DNA-duplex | Descriptor: | 12 BP DNA DUPLEX, 12 BP THF CONTAINING DNA DUPLEX, CULLIN-4B, ... | Authors: | Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H. | Deposit date: | 2011-09-09 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (7.4 Å) | Cite: | The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
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3MR6
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![BU of 3mr6 by Molmil](/molmil-images/mine/3mr6) | Human DNA polymerase eta - DNA ternary complex with a CPD 2bp upstream of the active site (TT4) | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*C*AP*TP*CP*AP*(TTD)P*AP*CP*GP*AP*GP*C)-3'), DNA (5'-D(*TP*CP*TP*CP*GP*TP*AP*AP*T)-3'), ... | Authors: | Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. | Deposit date: | 2010-04-28 | Release date: | 2010-06-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
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3MR2
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![BU of 3mr2 by Molmil](/molmil-images/mine/3mr2) | Human DNA polymerase eta in complex with normal DNA and incoming nucleotide (Nrm) | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*T*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | Authors: | Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. | Deposit date: | 2010-04-28 | Release date: | 2010-06-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
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3MR3
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![BU of 3mr3 by Molmil](/molmil-images/mine/3mr3) | Human DNA polymerase eta - DNA ternary complex with the 3'T of a CPD in the active site (TT1) | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*(TTD)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*CP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | Authors: | Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. | Deposit date: | 2010-04-28 | Release date: | 2010-06-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
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3MR5
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![BU of 3mr5 by Molmil](/molmil-images/mine/3mr5) | Human DNA polymerase eta - DNA ternary complex with a CPD 1bp upstream of the active site (TT3) | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*CP*GP*TP*CP*AP*TP*AP*A)-3'), DNA (5'-D(*TP*AP*AP*CP*(TTD)P*AP*TP*GP*AP*CP*GP*A)-3'), ... | Authors: | Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W. | Deposit date: | 2010-04-28 | Release date: | 2010-06-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
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8EBU
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![BU of 8ebu by Molmil](/molmil-images/mine/8ebu) | XPC release from Core7-XPA-DNA (Cy5) | Descriptor: | DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, DNA1, ... | Authors: | Kim, J, Yang, W. | Deposit date: | 2022-08-31 | Release date: | 2023-04-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair. Nature, 617, 2023
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8EBS
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![BU of 8ebs by Molmil](/molmil-images/mine/8ebs) | |
8EBT
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![BU of 8ebt by Molmil](/molmil-images/mine/8ebt) | |
8EBY
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![BU of 8eby by Molmil](/molmil-images/mine/8eby) | XPC release from Core7-XPA-DNA (AP) | Descriptor: | DNA, DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, ... | Authors: | Kim, J, Yang, W. | Deposit date: | 2022-08-31 | Release date: | 2023-04-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair. Nature, 617, 2023
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8EBV
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![BU of 8ebv by Molmil](/molmil-images/mine/8ebv) | |
8EBW
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![BU of 8ebw by Molmil](/molmil-images/mine/8ebw) | |
8EBX
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![BU of 8ebx by Molmil](/molmil-images/mine/8ebx) | |