6SW8
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![BU of 6sw8 by Molmil](/molmil-images/mine/6sw8) | Crystal structure of the NS1 (H7N1) RNA-binding domain | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Non-structural protein 1 | Authors: | Coste, F, Wacquiez, A, Marc, D, Castaing, B. | Deposit date: | 2019-09-20 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.933 Å) | Cite: | Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses, 12, 2020
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6SX2
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![BU of 6sx2 by Molmil](/molmil-images/mine/6sx2) | dsRNA recognition by R38AK41A mutant of H7N1 NS1 RNA Binding Domain | Descriptor: | 1,2-ETHANEDIOL, Non-structural protein 1, RNA (5'-R(*GP*GP*UP*AP*AP*CP*UP*GP*UP*UP*AP*CP*AP*GP*UP*UP*AP*CP*C)-3') | Authors: | Coste, F, Wacquiez, A, Marc, D, Castaing, B. | Deposit date: | 2019-09-24 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses, 12, 2020
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6SX0
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![BU of 6sx0 by Molmil](/molmil-images/mine/6sx0) | Specific dsRNA recognition by wild type H7N1 NS1 RNA-binding domain | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Non-structural protein 1, ... | Authors: | Coste, F, Wacquiez, A, Marc, D, Castaing, B. | Deposit date: | 2019-09-24 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses, 12, 2020
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6RNM
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![BU of 6rnm by Molmil](/molmil-images/mine/6rnm) | Crystal structure of a complex between the LlFpg protein, a THF-DNA and an inhibitor | Descriptor: | 6-azanyl-9~{H}-purine-8-thiol, DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), ... | Authors: | Coste, F, Goffinont, S, Castaing, B. | Deposit date: | 2019-05-09 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. Int J Mol Sci, 21, 2020
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6RP0
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![BU of 6rp0 by Molmil](/molmil-images/mine/6rp0) | The crystal structure of a complex between the LlFpg protein, a THF-DNA and an inhibitor | Descriptor: | 2,8-dithioxo-1,2,3,7,8,9-hexahydro-6H-purin-6-one, DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), ... | Authors: | Coste, F, Goffinont, S, Castaing, B. | Deposit date: | 2019-05-13 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. Int J Mol Sci, 21, 2020
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6RNR
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![BU of 6rnr by Molmil](/molmil-images/mine/6rnr) | The crystal structure of a complex between the LlFpg protein, a THF-DNA and an inhibitor | Descriptor: | 2-(trifluoromethyl)-9~{H}-purine-6-thiol, DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), ... | Authors: | Coste, F, Goffinont, S, Castaing, B. | Deposit date: | 2019-05-09 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. Int J Mol Sci, 21, 2020
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6ROK
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![BU of 6rok by Molmil](/molmil-images/mine/6rok) | The crystal structure of a complex between the LlFpg protein, a THF-DNA and an inhibitor | Descriptor: | 2,8-dithioxo-1,2,3,7,8,9-hexahydro-6H-purin-6-one, DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), ... | Authors: | Coste, F, Goffinont, S, Castaing, B. | Deposit date: | 2019-05-13 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. Int J Mol Sci, 21, 2020
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1MUL
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![BU of 1mul by Molmil](/molmil-images/mine/1mul) | Crystal structure of the E. coli HU alpha2 protein | Descriptor: | DNA binding protein HU-alpha | Authors: | Ramstein, J, Hervouet, N, Coste, F, Zelwer, C, Oberto, J, Castaing, B. | Deposit date: | 2002-09-24 | Release date: | 2003-08-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Evidence of a Thermal Unfolding Dimeric Intermediate for the Escherichia coli Histone-like HU Proteins: Thermodynamics and Structure. J.Mol.Biol., 331, 2003
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5LVT
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![BU of 5lvt by Molmil](/molmil-images/mine/5lvt) | |
3IE4
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![BU of 3ie4 by Molmil](/molmil-images/mine/3ie4) | b-glucan binding domain of Drosophila GNBP3 defines a novel family of pattern recognition receptor | Descriptor: | 1,2-ETHANEDIOL, Gram-Negative Binding Protein 3, ZINC ION | Authors: | Mishima, Y, Coste, F, Kellenberger, C, Roussel, A. | Deposit date: | 2009-07-22 | Release date: | 2009-08-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The N-terminal domain of drosophila gram-negative binding protein 3 (GNBP3) defines a novel family of fungal pattern recognition receptors To be Published
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1YCD
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![BU of 1ycd by Molmil](/molmil-images/mine/1ycd) | Crystal structure of yeast FSH1/YHR049W, a member of the serine hydrolase family | Descriptor: | 2-HYDROXY-4,5-DIOXOHEPTYL HYDROGEN PHOSPHONATE, Hypothetical 27.3 kDa protein in AAP1-SMF2 intergenic region | Authors: | Leulliot, N, Graille, M, Coste, F, Quevillon-Cheruel, S, Janin, J, van Tilbeurgh, H, Paris-Sud Yeast Structural Genomics (YSG) | Deposit date: | 2004-12-22 | Release date: | 2005-05-10 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family. Protein Sci., 14, 2005
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4P3V
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![BU of 4p3v by Molmil](/molmil-images/mine/4p3v) | |
2XZU
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![BU of 2xzu by Molmil](/molmil-images/mine/2xzu) | CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE WILD-TYPE LACTOCOCCUS LACTIS FPG (MUTM) AND AN OXIDIZED PYRIMIDINE CONTAINING DNA AT 310K | Descriptor: | 5'-D(*CP*TP*CP*TP*TP*TP*VETP*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*G*A)-3', FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE, ... | Authors: | Lebihan, Y.V, Izquierdo, M.A, Coste, F, Culard, F, Gehrke, T.H, Essalhi, K, Aller, P, Carrel, T, Castaing, B. | Deposit date: | 2010-11-29 | Release date: | 2011-10-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | 5-Hydroxy-5-Methylhydantoin DNA Lesion, a Molecular Trap for DNA Glycosylases Nucleic Acids Res., 39, 2011
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2XZF
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![BU of 2xzf by Molmil](/molmil-images/mine/2xzf) | CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE WILD-TYPE LACTOCOCCUS LACTIS FPG (MUTM) AND AN OXIDIZED PYRIMIDINE CONTAINING DNA AT 293K | Descriptor: | 5'-D(*CP*TP*CP*TP*TP*TP*VETP*TP*TP*TP*CP*TP*CP*GP)-3', 5'-D(*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*AP*GP*CP)-3', FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE, ... | Authors: | LeBihan, Y.V, Izquierdo, M.A, Coste, F, Culard, F, Gehrke, T.H, Essalhi, K, Aller, P, Carrel, T, Castaing, B. | Deposit date: | 2010-11-25 | Release date: | 2011-10-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | 5-Hydroxy-5-Methylhydantoin DNA Lesion, a Molecular Trap for DNA Glycosylases Nucleic Acids Res., 39, 2011
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7OQH
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![BU of 7oqh by Molmil](/molmil-images/mine/7oqh) | CryoEM structure of the transcription termination factor Rho from Mycobacterium tuberculosis | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Transcription termination factor Rho | Authors: | Saridakis, E, Vishwakarma, R, Lai Kee Him, J, Martin, K, Simon, I, Cohen-Gonsaud, M, Coste, F, Bron, P, Margeat, E, Boudvillain, M. | Deposit date: | 2021-06-03 | Release date: | 2022-02-09 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism. Commun Biol, 5, 2022
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2XZ8
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![BU of 2xz8 by Molmil](/molmil-images/mine/2xz8) | CRYSTAL STRUCTURE OF THE LFW ECTODOMAIN OF THE PEPTIDOGLYCAN RECOGNITION PROTEIN LF | Descriptor: | DI(HYDROXYETHYL)ETHER, PEPTIDOGLYCAN-RECOGNITION PROTEIN LF, SODIUM ION, ... | Authors: | Basbous, N, Coste, F, Leone, P, Vincentelli, R, Royet, J, Kellenberger, C, Roussel, A. | Deposit date: | 2010-11-24 | Release date: | 2011-04-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | The Drosophila Peptidoglycan-Recognition Protein Lf Interacts with Peptidoglycan-Recognition Protein Lc to Downregulate the Imd Pathway. Embo Rep., 12, 2011
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2XZ4
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![BU of 2xz4 by Molmil](/molmil-images/mine/2xz4) | Crystal structure of the LFZ ectodomain of the peptidoglycan recognition protein LF | Descriptor: | 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, COPPER (II) ION, ... | Authors: | Basbous, N, Coste, F, Leone, P, Vincentelli, R, Royet, J, Kellenberger, C, Roussel, A. | Deposit date: | 2010-11-23 | Release date: | 2011-04-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | The Drosophila Peptidoglycan-Recognition Protein Lf Interacts with Peptidoglycan-Recognition Protein Lc to Downregulate the Imd Pathway. Embo Rep., 12, 2011
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7OU3
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![BU of 7ou3 by Molmil](/molmil-images/mine/7ou3) | Crystal structure of Tga-AGOG, an 8-oxoguanine DNA glycosylase from Thermococcus gammatolerans | Descriptor: | CHLORIDE ION, GLYCEROL, N-glycosylase/DNA lyase | Authors: | Coste, F, Confalonieri, F, Castaing, B. | Deposit date: | 2021-06-11 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7OLI
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![BU of 7oli by Molmil](/molmil-images/mine/7oli) | Crystal structure of Pab-AGOG in complex with 8-oxoguanosine | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXY-8-OXOGUANOSINE, N-glycosylase/DNA lyase | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-05-20 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7OLB
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![BU of 7olb by Molmil](/molmil-images/mine/7olb) | Crystal structure of Pab-AGOG, an 8-oxoguanine DNA glycosylase from Pyrococcus abyssi | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-05-19 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7OUE
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![BU of 7oue by Molmil](/molmil-images/mine/7oue) | Crystal structure of a trapped Pab-AGOG/single-standed DNA covalent intermediate | Descriptor: | DNA (5'-D(*TP*TP*TP*(PED)P*TP*TP*TP*CP*T)-3'), N-glycosylase/DNA lyase, PHOSPHATE ION, ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-06-11 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7P0W
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![BU of 7p0w by Molmil](/molmil-images/mine/7p0w) | Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing thymine opposite to lesion) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(PED)P*TP*TP*TP*CP*T)-3'), ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-06-30 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7OY7
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![BU of 7oy7 by Molmil](/molmil-images/mine/7oy7) | Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(PED)P*TP*TP*TP*CP*T)-3'), ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-06-23 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7P8L
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![BU of 7p8l by Molmil](/molmil-images/mine/7p8l) | Crystal structure of Pyrococcus abyssi 8-oxoguanine DNA glycosylase (PabAGOG) in complex with dsDNA containing cytosine opposite to 8-oxoG | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(8OG)P*TP*TP*TP*CP*T)-3'), ... | Authors: | Coste, F, Flament, D, Castaing, B. | Deposit date: | 2021-07-23 | Release date: | 2022-08-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7P9Z
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![BU of 7p9z by Molmil](/molmil-images/mine/7p9z) | Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing adenine opposite to lesion) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(PED)*TP*TP*TP*CP*T)-3'), ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-07-28 | Release date: | 2022-08-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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