6RP0

The crystal structure of a complex between the LlFpg protein, a THF-DNA and an inhibitor

Summary for 6RP0

• Entry DOI: 10.2210/pdb6rp0/pdb
• Descriptor: FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE, DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), ... (6 entities in total)
• Functional Keywords: dna glycosylase complex, inhibitor, hydrolase
• Biological source: Lactococcus lactis subsp. cremoris; More
• Total number of polymer chains: 4
• Total formula weight: 43873.66

Authors

Coste, F.,Goffinont, S.,Castaing, B. (deposition date: 2019-05-13, release date: 2020-04-15, Last modification date: 2024-01-24)

• Primary citation: Rieux, C.,Goffinont, S.,Coste, F.,Tber, Z.,Cros, J.,Roy, V.,Guerin, M.,Gaudon, V.,Bourg, S.,Biela, A.,Aucagne, V.,Agrofoglio, L.,Garnier, N.,Castaing, B.; Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights.; Int J Mol Sci, 21:-, 2020; PubMed: 32192183; DOI: 10.3390/ijms21062058

Experimental method

X-RAY DIFFRACTION (2.25 Å)