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HIV-1 PROTEASE V82F/I84V DOUBLE MUTANT/TIPRANAVIR COMPLEX
Descriptor:	N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE, PROTEIN (HIV-1 PROTEASE)
Authors:	Watenpaugh, K.D, Janakiraman, M.N.
Deposit date:	1999-10-05
Release date:	1999-10-12
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Structure-based design of HIV protease inhibitors: sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones as non-peptidic inhibitors. J.Med.Chem., 39, 1996

Crystal structure of Importin-beta and SREBP-2 complex
Descriptor:	Importin beta-1 subunit, Sterol regulatory element binding protein-2
Authors:	Lee, S.J, Sekimoto, T, Yamashita, E, Nagoshi, E, Nakagawa, A, Imamoto, N, Yoshimura, M, Sakai, H, Tsukihara, T, Yoneda, Y.
Deposit date:	2003-08-26
Release date:	2003-12-09
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	The Structure of Importin-beta Bound to SREBP-2: Nuclear Import of a Transcription Factor Science, 302, 2003

HIV-1 PROTEASE COMPLEX WITH U095438 [3-[1-(4-BROMOPHENYL) ISOBUTYL]-4-HYDROXYCOUMARIN
Descriptor:	3-[1-(4-BROMO-PHENYL)-2-METHYL-PROPYL]-4-HYDROXY-CHROMEN-2-ONE, HIV-1 PROTEASE
Authors:	Watenpaugh, K.D, Mulichak, A.M, Janakiraman, M.N.
Deposit date:	1996-03-04
Release date:	1996-10-14
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.22 Å)
Cite:	Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitors. J.Med.Chem., 38, 1995