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6Y56
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BU of 6y56 by Molmil
MenT4, nucleotidyltransferase toxin Rv2826c from Mycobacterium tuberculosis H37Rv
Descriptor: Uncharacterized protein
Authors:Usher, B, Blower, T.R.
Deposit date:2020-02-24
Release date:2020-09-16
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:A nucleotidyltransferase toxin inhibits growth of Mycobacterium tuberculosis through inactivation of tRNA acceptor stems.
Sci Adv, 6, 2020
7P9K
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BU of 7p9k by Molmil
BrxU, GmrSD-family Type IV restriction enzyme
Descriptor: CHLORIDE ION, DUF262 domain-containing protein, GLYCEROL, ...
Authors:Picton, D.M, Luyten, Y, Morgan, R.D, Nelson, A, Smith, D.L, Dryden, D.T.F, Hinton, J.C.D, Blower, T.R.
Deposit date:2021-07-27
Release date:2021-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses.
Nucleic Acids Res., 49, 2021
7P9M
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BU of 7p9m by Molmil
BrxU, GmrSD-family Type IV restriction enzyme
Descriptor: CHLORIDE ION, DUF262 domain-containing protein, SULFATE ION
Authors:Picton, D.M, Luyten, Y, Morgan, R.D, Nelson, A, Smith, D.L, Dryden, D.T.F, Hinton, J.C.D, Blower, T.R.
Deposit date:2021-07-27
Release date:2021-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses.
Nucleic Acids Res., 49, 2021
7QFN
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BU of 7qfn by Molmil
Human Topoisomerase II Beta ATPase ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA topoisomerase 2-beta, MAGNESIUM ION, ...
Authors:Ling, E.M, Basle, A, Cowell, I.G, Blower, T.R, Austin, C.A.
Deposit date:2021-12-06
Release date:2022-05-25
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.621 Å)
Cite:A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193.
Structure, 30, 2022
7QFO
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BU of 7qfo by Molmil
Human Topoisomerase II Beta ATPase AMPPNP
Descriptor: ALANINE, DNA topoisomerase 2-beta, MAGNESIUM ION, ...
Authors:Ling, E.M, Basle, A, Cowell, I.G, Blower, T.R, Austin, C.A.
Deposit date:2021-12-06
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193.
Structure, 30, 2022
7ZBG
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BU of 7zbg by Molmil
Human Topoisomerase II Beta ATPase ADP
Descriptor: 4-[(2S,3R)-3-[3,5-bis(oxidanylidene)piperazin-1-ium-1-yl]butan-2-yl]piperazin-4-ium-2,6-dione, ADENOSINE-5'-DIPHOSPHATE, DNA topoisomerase 2-beta, ...
Authors:Ling, E.M, Basle, A, Cowell, I.G, Blower, T.R, Austin, C.A.
Deposit date:2022-03-23
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193.
Structure, 30, 2022
7B5J
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BU of 7b5j by Molmil
Anti-CRISPR associated (Aca) protein, Aca2
Descriptor: Anti-CRISPR associated (Aca) protein, Aca2, GLYCEROL
Authors:Usher, B, Birkholz, N, Fineran, P.C, Blower, T.R.
Deposit date:2020-12-03
Release date:2021-06-23
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Crystal structure of the anti-CRISPR repressor Aca2.
J.Struct.Biol., 213, 2021
4RMO
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BU of 4rmo by Molmil
Crystal Structure of the CptIN Type III Toxin-Antitoxin System from Eubacterium rectale
Descriptor: CALCIUM ION, CptN Toxin, RNA (45-MER)
Authors:Rao, F, Voss, J.E, Short, F.L, Luisi, B.F.
Deposit date:2014-10-21
Release date:2015-09-30
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Co-evolution of quaternary organization and novel RNA tertiary interactions revealed in the crystal structure of a bacterial protein-RNA toxin-antitoxin system.
Nucleic Acids Res., 43, 2015
8VVN
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BU of 8vvn by Molmil
Cryo-EM structure of a type I ZorAB complex from Shewanella sp. strain ANA-3
Descriptor: Chemotaxis protein MotB-related protein, MotA/TolQ/ExbB proton channel domain-containing protein, SODIUM ION
Authors:Deme, J.C, Lea, S.M.
Deposit date:2024-01-31
Release date:2025-02-05
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Modularity of Zorya defense systems during phage inhibition.
Nat Commun, 16, 2025
8VVI
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BU of 8vvi by Molmil
Cryo-EM structure of a type II ZorAB complex from Sulfuricurvum kujiense
Descriptor: MotA/TolQ/ExbB proton channel domain-containing protein, Motility protein B-like N-terminal domain-containing protein
Authors:Deme, J.C, Lea, S.M.
Deposit date:2024-01-31
Release date:2025-02-05
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Modularity of Zorya defense systems during phage inhibition.
Nat Commun, 16, 2025
8W35
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BU of 8w35 by Molmil
Aca2 from Pectobacterium phage ZF40 bound to RNA
Descriptor: Anti-CRISPR associated (Aca) protein, Aca2, IR2 and IR-RBS RNA
Authors:Wilkinson, M.E, Birkholz, N, Kimanius, D, Fineran, P.C.
Deposit date:2024-02-21
Release date:2024-07-24
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein.
Nature, 631, 2024
9EWZ
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BU of 9ewz by Molmil
Cryo-EM structure of the E. coli BrxX methyltransferase in complex with DNA
Descriptor: Adenine-specific methyltransferase BrxX, DNA (26-MER) with BREX binding site GGTAAG, MAGNESIUM ION, ...
Authors:Adams, M.C, Ghilarov, D.
Deposit date:2024-04-05
Release date:2025-03-05
Method:ELECTRON MICROSCOPY (2.22 Å)
Cite:Molecular basis of foreign DNA recognition by BREX anti-phage immunity system.
Nat Commun, 16, 2025
9EX7
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BU of 9ex7 by Molmil
Cryo-EM structure of the E. coli BrxX methyltransferase in complex with Ocr
Descriptor: Adenine-specific methyltransferase BrxX, MAGNESIUM ION, Protein Ocr, ...
Authors:Adams, M.C, Ghilarov, D.
Deposit date:2024-04-05
Release date:2025-03-05
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Molecular basis of foreign DNA recognition by BREX anti-phage immunity system.
Nat Commun, 16, 2025
9EXH
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BU of 9exh by Molmil
Cryo-EM structure of the Apo E. coli BrxX methyltransferase
Descriptor: Adenine-specific methyltransferase BrxX
Authors:Adams, M.C, Ghilarov, D.
Deposit date:2024-04-08
Release date:2025-03-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular basis of foreign DNA recognition by BREX anti-phage immunity system.
Nat Commun, 16, 2025
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