7QFN
Human Topoisomerase II Beta ATPase ADP
Summary for 7QFN
Entry DOI | 10.2210/pdb7qfn/pdb |
Descriptor | DNA topoisomerase 2-beta, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ... (5 entities in total) |
Functional Keywords | dna topoisomerase ii beta, human, atpase domain, top2b, dna binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 46581.54 |
Authors | Ling, E.M.,Basle, A.,Cowell, I.G.,Blower, T.R.,Austin, C.A. (deposition date: 2021-12-06, release date: 2022-05-25, Last modification date: 2024-06-19) |
Primary citation | Ling, E.M.,Basle, A.,Cowell, I.G.,van den Berg, B.,Blower, T.R.,Austin, C.A. A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193. Structure, 30:1129-1145.e3, 2022 Cited by PubMed: 35660158DOI: 10.1016/j.str.2022.05.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.621 Å) |
Structure validation
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