1MVI
| N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA, NMR, 15 STRUCTURES | Descriptor: | MVIIA | Authors: | Nielsen, K.J, Thomas, L, Lewis, R.J, Alewood, P.F, Craik, D.J. | Deposit date: | 1996-08-02 | Release date: | 1997-08-12 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202. J.Mol.Biol., 263, 1996
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1MVJ
| N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA NMR, 15 STRUCTURES | Descriptor: | SVIB | Authors: | Nielsen, K.J, Thomas, L, Lewis, R.J, Alewood, P.F, Craik, D.J. | Deposit date: | 1996-08-02 | Release date: | 1997-08-12 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202. J.Mol.Biol., 263, 1996
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1N1U
| NMR structure of [Ala1,15]kalata B1 | Descriptor: | kalata B1 | Authors: | Daly, N.L, Clark, R.J, Craik, D.J. | Deposit date: | 2002-10-20 | Release date: | 2003-02-25 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Disulfide Folding Pathways of Cystine Knot Proteins. TYING THE KNOT WITHIN THE CIRCULAR BACKBONE OF THE CYCLOTIDES J.Biol.Chem., 278, 2003
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1MR4
| Solution Structure of NaD1 from Nicotiana alata | Descriptor: | Nicotiana alata plant defensin 1 (NaD1) | Authors: | Lay, F.T, Schirra, H.J, Scanlon, M.J, Anderson, M.A, Craik, D.J. | Deposit date: | 2002-09-18 | Release date: | 2003-09-18 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | The Three-dimensional Solution Structure of NaD1, a New Floral Defensin from Nicotiana alata and its Application to a Homology Model of the Crop Defense Protein alfAFP J.MOL.BIOL., 325, 2003
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8TYI
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8FLP
| NMR Solution Structure of LvIC analogue | Descriptor: | Alpha-conotoxin LvIC analogue | Authors: | Harvey, P.J, Craik, D.J. | Deposit date: | 2022-12-22 | Release date: | 2023-02-08 | Last modified: | 2023-02-22 | Method: | SOLUTION NMR | Cite: | Discovery, Characterization, and Engineering of LvIC, an alpha 4/4-Conotoxin That Selectively Blocks Rat alpha 6/ alpha 3 beta 4 Nicotinic Acetylcholine Receptors. J.Med.Chem., 66, 2023
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6MJD
| NMR Solution structure of GIIIC | Descriptor: | ARG-ASP-CYS-CYS-THR-HYP-HYP-LYS-LYS-CYS-LYS-ASP-ARG-ARG-CYS-LYS-HYP-LEU-LYS-CYS-CYS-ALA-NH2 | Authors: | Harvey, P.J, Durek, T, Craik, D.J. | Deposit date: | 2018-09-20 | Release date: | 2018-11-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | NMR Structure of mu-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced NaVChannel Potency. Molecules, 23, 2018
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1GIB
| MU-CONOTOXIN GIIIB, NMR | Descriptor: | MU-CONOTOXIN GIIIB | Authors: | Hill, J.M, Alewood, P.F, Craik, D.J. | Deposit date: | 1996-04-17 | Release date: | 1996-11-08 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels. Biochemistry, 35, 1996
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1HX2
| SOLUTION STRUCTURE OF BSTI, A TRYPSIN INHIBITOR FROM BOMBINA BOMBINA. | Descriptor: | BSTI | Authors: | Rosengren, K.J, Daly, N.L, Scanlon, M.J, Craik, D.J. | Deposit date: | 2001-01-11 | Release date: | 2001-01-24 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of BSTI: a new trypsin inhibitor from skin secretions of Bombina bombina. Biochemistry, 40, 2001
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1TIH
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6U7Q
| NMR solution structure of SFTI-R10 | Descriptor: | GLY-ARG-CYS-THR-LYS-SER-ILE-PRO-PRO-ARG-CYS-PHE-PRO-ASP inhibitor | Authors: | White, A.M, Harvey, P.J, Durek, T, Craik, D.J. | Deposit date: | 2019-09-03 | Release date: | 2020-04-22 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides. Angew.Chem.Int.Ed.Engl., 59, 2020
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6U24
| NMR solution structure of triazole bridged SFTI-1 | Descriptor: | 1-methyl-1H-1,2,3-triazole, GLY-ARG-ALA-THR-LYS-SER-ILE-PRO-PRO-ILE-ALA-PHE-PRO-ASP | Authors: | White, A.M, Harvey, P.J, Durek, T, Craik, D.J. | Deposit date: | 2019-08-19 | Release date: | 2020-07-01 | Last modified: | 2020-07-15 | Method: | SOLUTION NMR | Cite: | Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides. Angew.Chem.Int.Ed.Engl., 59, 2020
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6U7U
| NMR solution structure of triazole bridged matriptase inhibitor | Descriptor: | 1-methyl-1H-1,2,3-triazole, GLY-ARG-ALA-THR-LYS-SER-ILE-PRO-PRO-ARG-ALA-PHE-PRO-ASP | Authors: | White, A.M, Harvey, P.J, Durek, T, Craik, D.J. | Deposit date: | 2019-09-03 | Release date: | 2020-04-22 | Last modified: | 2020-07-15 | Method: | SOLUTION NMR | Cite: | Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides. Angew.Chem.Int.Ed.Engl., 59, 2020
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6U7S
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6U7W
| NMR solution structure of a triazole bridged KLK7 inhibitor | Descriptor: | 1-methyl-1H-1,2,3-triazole, GLY-LYS-ALA-LEU-PHE-SER-ASN-PRO-PRO-ILE-ALA-PHE-PRO-ASN | Authors: | White, A.M, Harvey, P.J, Durek, T, Craik, D.J. | Deposit date: | 2019-09-03 | Release date: | 2020-04-22 | Last modified: | 2020-07-15 | Method: | SOLUTION NMR | Cite: | Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides. Angew.Chem.Int.Ed.Engl., 59, 2020
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6U22
| Crystal structure of SFTI-triazole inhibitor in complex with beta-trypsin | Descriptor: | 1-methyl-1H-1,2,3-triazole, CALCIUM ION, Cationic trypsin, ... | Authors: | White, A.M, King, G.J, Durek, T, Craik, D.J. | Deposit date: | 2019-08-19 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides. Angew.Chem.Int.Ed.Engl., 59, 2020
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2AK0
| Structure of cyclic conotoxin MII-7 | Descriptor: | Alpha-conotoxin MII | Authors: | Clark, R.J, Fischer, H, Dempster, L, Daly, N.L, Rosengren, K.J, Nevin, S.T, Meunier, F.A, Adams, D.J, Craik, D.J. | Deposit date: | 2005-08-02 | Release date: | 2005-09-06 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the {alpha}-conotoxin MII. Proc.Natl.Acad.Sci.USA, 102, 2005
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2AJW
| Structure of the cyclic conotoxin MII-6 | Descriptor: | Alpha-conotoxin MII | Authors: | Clark, R.J, Fischer, H, Dempster, L, Daly, N.L, Rosengren, K.J, Nevin, S.T, Meunier, F.A, Adams, D.J, Craik, D.J. | Deposit date: | 2005-08-02 | Release date: | 2005-09-06 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the {alpha}-conotoxin MII. Proc.Natl.Acad.Sci.USA, 102, 2005
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1R9I
| NMR Solution Structure of PIIIA toxin, NMR, 20 structures | Descriptor: | Mu-conotoxin PIIIA | Authors: | Nielsen, K.J, Watson, M, Adams, D.J, Hammarstrom, A.K, Gage, P.W, Hill, J.M, Craik, D.J, Thomas, L, Adams, D, Alewood, P.F, Lewis, R.J. | Deposit date: | 2003-10-30 | Release date: | 2003-11-18 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels J.Biol.Chem., 277, 2002
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1RMK
| Solution structure of conotoxin MrVIB | Descriptor: | Mu-O-conotoxin MrVIB | Authors: | Daly, N.L, Ekberg, J.A, Thomas, L, Adams, D.J, Lewis, R.J, Craik, D.J. | Deposit date: | 2003-11-28 | Release date: | 2004-09-07 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Structures of muO-conotoxins from Conus marmoreus. Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons J.Biol.Chem., 279, 2004
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6U7X
| NMR solution structure of triazole bridged plasmin inhibitor | Descriptor: | 1-methyl-1H-1,2,3-triazole, GLY-ARG-ALA-TYR-LYS-SER-LYS-PRO-PRO-ILE-ALA-PHE-PRO-ASP | Authors: | White, A.M, Harvey, P.J, Wang, C.K, Durek, T, Craik, D.J. | Deposit date: | 2019-09-03 | Release date: | 2020-04-22 | Last modified: | 2020-07-15 | Method: | SOLUTION NMR | Cite: | Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides. Angew.Chem.Int.Ed.Engl., 59, 2020
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6U7R
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1IEN
| SOLUTION STRUCTURE OF TIA | Descriptor: | PROTEIN TIA | Authors: | Sharpe, I.A, Gehrmann, J, Loughnan, M.L, Thomas, L, Adams, D.A, Atkins, A, Palant, E, Craik, D.J, Adams, D.J, Alewood, P.F, Lewis, R.J. | Deposit date: | 2001-04-10 | Release date: | 2002-04-03 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nat.Neurosci., 4, 2001
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1IEO
| SOLUTION STRUCTURE OF MRIB-NH2 | Descriptor: | PROTEIN MRIB-NH2 | Authors: | Sharpe, I.A, Gehrmann, J, Loughnan, M.L, Thomas, L, Adams, D.A, Atkins, A, Palant, E, Craik, D.J, Adams, D.J, Alewood, P.F, Lewis, R.J. | Deposit date: | 2001-04-10 | Release date: | 2002-04-03 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nat.Neurosci., 4, 2001
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6VH8
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