1T01
 
 | | Vinculin complexed with the VBS1 helix from talin | | Descriptor: | Talin 1, unnamed protein product | | Authors: | Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J. | | Deposit date: | 2004-04-07 | | Release date: | 2004-08-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
Embo J., 23, 2004
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2KMC
 | | Solution Structure of the N-terminal domain of kindlin-1 | | Descriptor: | Fermitin family homolog 1 | | Authors: | Goult, B.T, Bate, N, Roberts, G.C, Barsukov, I.L, Critchley, D.R. | | Deposit date: | 2009-07-27 | | Release date: | 2009-10-06 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The Structure of the N-Terminus of Kindlin-1: A Domain Important for alphaIIbbeta3 Integrin Activation
J.Mol.Biol., 394, 2009
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2KC1
 | | NMR structure of the F0 domain (residues 0-85) of the talin ferm domain | | Descriptor: | MKIAA1027 protein | | Authors: | Goult, B.T, Elliott, P.R, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | | Deposit date: | 2008-12-13 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
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2KVP
 | | Solution Structure of the R10 Domain of Talin | | Descriptor: | Talin-1 | | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R, Barsukov, I.L, Roberts, G.C. | | Deposit date: | 2010-03-24 | | Release date: | 2010-05-05 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
Febs Lett., 584, 2010
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2L10
 | | Solution Structure of the R6 Domain of Talin | | Descriptor: | Talin-1 | | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Roberts, G.C.K, Barsukov, I.L, Critchley, D.R. | | Deposit date: | 2010-07-22 | | Release date: | 2011-08-31 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
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2JSW
 | | Solution Structure of the R13 Domain of Talin | | Descriptor: | Talin-1 | | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R.C, Barsukov, I.L. | | Deposit date: | 2007-07-17 | | Release date: | 2008-01-29 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The structure of the C-terminal actin-binding domain of talin.
Embo J., 27, 2007
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2LQG
 | | Solution Structure of the R4 domain of talin | | Descriptor: | Talin-1 | | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Roberts, G.C.K, Barsukov, I.L, Critchley, D.R. | | Deposit date: | 2012-03-06 | | Release date: | 2013-02-13 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover.
J.Biol.Chem., 288, 2013
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2L7N
 | | Solution Structure of the R5 Domain of Talin | | Descriptor: | Talin-1 | | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Barsukov, I.L, Roberts, G.C.K, Critchley, D.R. | | Deposit date: | 2010-12-14 | | Release date: | 2011-12-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
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2KBB
 | | Solution Structure of the R9 Domain of Talin | | Descriptor: | Talin-1 | | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R, Barsukov, I.L. | | Deposit date: | 2008-11-24 | | Release date: | 2009-03-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The structure of an interdomain complex that regulates talin activity.
J.Biol.Chem., 284, 2009
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2KC2
 | | NMR structure of the F1 domain (residues 86-202) of the talin | | Descriptor: | Talin-1 | | Authors: | Goult, B.T, Elliott, P.R, Roberts, G.C.K, Critchely, D.R, Barsukov, I.L. | | Deposit date: | 2008-12-13 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
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2KGX
 | | HADDOCK structure of the talin F3 domain in complex with talin 1655-1822 | | Descriptor: | MKIAA1027 protein, Talin-1 | | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R, Barsukov, I.L. | | Deposit date: | 2009-03-23 | | Release date: | 2009-03-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The structure of an interdomain complex that regulates talin activity.
J.Biol.Chem., 284, 2009
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2KMA
 | | NMR structure of the F0F1 double domain (residues 1-202) of the talin ferm domain | | Descriptor: | Talin 1 | | Authors: | Goult, B.T, Elliott, P.R, Bate, N, Roberts, G.C, Critchley, D.R, Barsukov, I.L. | | Deposit date: | 2009-07-25 | | Release date: | 2010-03-02 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 2010
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2L7A
 | | Solution Structure of the R3 Domain of Talin | | Descriptor: | Talin-1 | | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Roberts, G.C.K, Barsukov, I.L, Critchley, D.R. | | Deposit date: | 2010-12-06 | | Release date: | 2011-12-21 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
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2K00
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5G4X
 | | The crystal structure of the SHANK3 N-terminus | | Descriptor: | 1,2-ETHANEDIOL, SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 | | Authors: | Zacharchenko, T, Barsukov, I. | | Deposit date: | 2016-05-17 | | Release date: | 2017-01-25 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.166 Å) | | Cite: | SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.
Nat. Cell Biol., 19, 2017
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3DYJ
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1LUD
 | | SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES | | Descriptor: | 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Polshakov, V.I, Smirnov, E.G, Birdsall, B, Kelly, G, Feeney, J. | | Deposit date: | 2002-05-22 | | Release date: | 2002-12-18 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH
J.Biomol.Nmr, 24, 2002
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1BZF
 | | NMR SOLUTION STRUCTURE AND DYNAMICS OF THE COMPLEX OF LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE WITH THE NEW LIPOPHILIC ANTIFOLATE DRUG TRIMETREXATE, 22 STRUCTURES | | Descriptor: | DIHYDROFOLATE REDUCTASE, TRIMETREXATE | | Authors: | Polshakov, V.I, Birdsall, B, Frenkiel, T.A, Gargaro, A.R, Feeney, J. | | Deposit date: | 1998-10-28 | | Release date: | 1999-05-18 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.
Protein Sci., 8, 1999
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