2NVU
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![BU of 2nvu by Molmil](/molmil-images/mine/2nvu) | Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera, ... | Authors: | Huang, D.T, Hunt, H.W, Zhuang, M, Ohi, M.D, Holton, J.M, Schulman, B.A. | Deposit date: | 2006-11-13 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity. Nature, 445, 2007
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1U68
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![BU of 1u68 by Molmil](/molmil-images/mine/1u68) | DHNA 7,8 DIHYDRONEOPTERIN COMPLEX | Descriptor: | 2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE, Dihydroneopterin aldolase | Authors: | Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A. | Deposit date: | 2004-07-29 | Release date: | 2004-10-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization. J.MED.CHEM., 47, 2004
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2NZJ
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![BU of 2nzj by Molmil](/molmil-images/mine/2nzj) | The crystal structure of REM1 in complex with GDP | Descriptor: | CHLORIDE ION, GTP-binding protein REM 1, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Turnbull, A.P, Papagrigoriou, E, Ugochukwu, E, Elkins, J.M, Soundararajan, M, Yang, X, Gorrec, F, Umeano, C, Salah, E, Burgess, N, Johansson, C, Berridge, G, Gileadi, O, Bray, J, Marsden, B, Watts, S, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C.H, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2006-11-23 | Release date: | 2006-12-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of REM1 in complex with GDP To be Published
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1MUF
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![BU of 1muf by Molmil](/molmil-images/mine/1muf) | Structure of histone H3 K4-specific methyltransferase SET7/9 | Descriptor: | SET9 | Authors: | Jacobs, S.A, Harp, J.M, Devarakonda, S, Kim, Y, Rastinejad, F, Khorasanizadeh, S. | Deposit date: | 2002-09-23 | Release date: | 2002-11-06 | Last modified: | 2011-11-16 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | The active site of the SET domain is constructed on a knot Nat.Struct.Biol., 9, 2002
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1MLX
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![BU of 1mlx by Molmil](/molmil-images/mine/1mlx) | Crystal Structure Analysis of a 2'-O-[2-(Methylthio)-ethyl]-Modified Oligodeoxynucleotide Duplex | Descriptor: | 5'-D(*GP*CP*GP*TP*AP*SMTP*AP*CP*GP*C)-3' | Authors: | Prakash, T.P, Manoharan, M, Kawasaki, A.M, Fraser, A.S, Lesnik, E.A, Sioufi, N, Leeds, J.M, Teplova, M, Egli, M. | Deposit date: | 2002-08-31 | Release date: | 2002-12-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | 2'-O-[2-(Methylthio)ethyl]-Modified Oligonucleotide: An Analogue of 2'-O-[2-(Methoxy)-ethyl]-Modified
Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA Biochemistry, 41, 2002
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1TYF
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![BU of 1tyf by Molmil](/molmil-images/mine/1tyf) | |
1TOK
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![BU of 1tok by Molmil](/molmil-images/mine/1tok) | Maleic acid-bound structure of SRHEPT mutant of E. coli aspartate aminotransferase | Descriptor: | Aspartate aminotransferase, MALEIC ACID | Authors: | Chow, M.A, McElroy, K.E, Corbett, K.D, Berger, J.M, Kirsch, J.F. | Deposit date: | 2004-06-14 | Release date: | 2004-10-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase Biochemistry, 43, 2004
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2OO6
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![BU of 2oo6 by Molmil](/molmil-images/mine/2oo6) | Crystal structure of putative L-alanine-DL-glutamate epimerase from Burkholderia xenovorans strain LB400 | Descriptor: | Putative L-alanine-DL-glutamate epimerase, SULFATE ION | Authors: | Bonanno, J.B, Dickey, M, Bain, K.T, Wu, B, Sridhar, V, Freeman, J, Smyth, L, Atwell, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-01-25 | Release date: | 2007-02-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of putative L-alanine-DL-glutamate epimerase from Burkholderia xenovorans strain LB400 To be Published
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2OOG
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![BU of 2oog by Molmil](/molmil-images/mine/2oog) | Crystal structure of glycerophosphoryl diester phosphodiesterase from Staphylococcus aureus | Descriptor: | GLYCEROL, Glycerophosphoryl diester phosphodiesterase, SULFATE ION, ... | Authors: | Patskovsky, Y, Fedorov, E, Toro, R, Sauder, J.M, Smith, D, Freeman, J, Maletic, M, Powell, A, Gheyi, T, Wasserman, S.R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-01-25 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of Glycerophosphoryl Diester Phosphodiesterase from Staphylococcus Aureus To be Published
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1TN9
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![BU of 1tn9 by Molmil](/molmil-images/mine/1tn9) | |
1TOJ
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![BU of 1toj by Molmil](/molmil-images/mine/1toj) | Hydrocinnamic acid-bound structure of SRHEPT mutant of E. coli aspartate aminotransferase | Descriptor: | Aspartate aminotransferase, HYDROCINNAMIC ACID | Authors: | Chow, M.A, McElroy, K.E, Corbett, K.D, Berger, J.M, Kirsch, J.F. | Deposit date: | 2004-06-14 | Release date: | 2004-10-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase Biochemistry, 43, 2004
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1TP9
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![BU of 1tp9 by Molmil](/molmil-images/mine/1tp9) | PRX D (type II) from Populus tremula | Descriptor: | SULFATE ION, peroxiredoxin | Authors: | Echalier, A, Trivelli, X, Corbier, C, Rouhier, N, Walker, O, Tsan, P, Jacquot, J.P, Krimm, I, Lancelin, J.M. | Deposit date: | 2004-06-16 | Release date: | 2005-04-26 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Crystal structure and solution NMR dynamics of a D (type II) peroxiredoxin glutaredoxin and thioredoxin dependent: a new insight into the peroxiredoxin oligomerism Biochemistry, 44, 2005
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2P5Z
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![BU of 2p5z by Molmil](/molmil-images/mine/2p5z) | The E. coli c3393 protein is a component of the type VI secretion system and exhibits structural similarity to T4 bacteriophage tail proteins gp27 and gp5 | Descriptor: | Type VI secretion system component | Authors: | Ramagopal, U.A, Bonanno, J.B, Sridhar, V, Lau, C, Toro, R, Gheyi, T, Maletic, M, Freeman, J.C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-03-16 | Release date: | 2007-04-03 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin. Proc.Natl.Acad.Sci.Usa, 106, 2009
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1TOI
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![BU of 1toi by Molmil](/molmil-images/mine/1toi) | Hydrocinnamic acid-bound structure of Hexamutant + A293D mutant of E. coli aspartate aminotransferase | Descriptor: | Aspartate aminotransferase, HYDROCINNAMIC ACID | Authors: | Chow, M.A, McElroy, K.E, Corbett, K.D, Berger, J.M, Kirsch, J.F. | Deposit date: | 2004-06-14 | Release date: | 2004-10-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase Biochemistry, 43, 2004
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1MM2
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![BU of 1mm2 by Molmil](/molmil-images/mine/1mm2) | Solution structure of the 2nd PHD domain from Mi2b | Descriptor: | Mi2-beta, ZINC ION | Authors: | Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P. | Deposit date: | 2002-09-02 | Release date: | 2003-07-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Engineering a Protein Scaffold from a PHD Finger structure, 11, 2003
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2PJD
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![BU of 2pjd by Molmil](/molmil-images/mine/2pjd) | Crystal structure of 16S rRNA methyltransferase RsmC | Descriptor: | Ribosomal RNA small subunit methyltransferase C | Authors: | Sunita, S, Purta, E, Durawa, M, Tkaczuk, K.L, Bujnicki, J.M, Sivaraman, J. | Deposit date: | 2007-04-16 | Release date: | 2007-07-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC Nucleic Acids Res., 35, 2007
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1MQ2
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![BU of 1mq2 by Molmil](/molmil-images/mine/1mq2) | Human DNA Polymerase Beta Complexed With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine and dAMP | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(2DA))-3', ... | Authors: | Krahn, J.M, Beard, W.A, Miller, H, Grollman, A.P, Wilson, S.H. | Deposit date: | 2002-09-13 | Release date: | 2003-01-28 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of DNA Polymerase beta with the Mutagenic DNA Lesion 8-oxodeoxyguanine Reveals
Structural Insights into its Coding Potential Structure, 11, 2003
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2PFP
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![BU of 2pfp by Molmil](/molmil-images/mine/2pfp) | DNA Polymerase lambda in complex with DNA and dCTP | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ... | Authors: | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | Deposit date: | 2007-04-05 | Release date: | 2007-05-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
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2PTF
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![BU of 2ptf by Molmil](/molmil-images/mine/2ptf) | Crystal structure of protein MTH_863 from Methanobacterium thermoautotrophicum bound to FMN | Descriptor: | FLAVIN MONONUCLEOTIDE, Uncharacterized protein MTH_863 | Authors: | Bonanno, J.B, Rutter, M, Bain, K.T, Iizuka, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-05-08 | Release date: | 2007-05-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of protein MTH_863 from Methanobacterium thermoautotrophicum bound to FMN. To be Published
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1OW8
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![BU of 1ow8 by Molmil](/molmil-images/mine/1ow8) | Paxillin LD2 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase | Descriptor: | Focal adhesion kinase 1, Paxillin | Authors: | Hoellerer, M.K, Noble, M.E.M, Labesse, G, Werner, J.M, Arold, S.T. | Deposit date: | 2003-03-28 | Release date: | 2003-10-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Molecular Recognition of Paxillin LD Motifs
by the Focal Adhesion Targeting Domain Structure, 11, 2003
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2PMR
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![BU of 2pmr by Molmil](/molmil-images/mine/2pmr) | Crystal structure of a protein of unknown function from Methanobacterium thermoautotrophicum | Descriptor: | Uncharacterized protein | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Wu, B, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-04-23 | Release date: | 2007-05-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Crystal structure of a protein of unknown function from Methanobacterium thermoautotrophicum. To be Published
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2PL7
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![BU of 2pl7 by Molmil](/molmil-images/mine/2pl7) | |
2PQL
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![BU of 2pql by Molmil](/molmil-images/mine/2pql) | Crystal Structure of Anopheles gambiae D7R4-tryptamine complex | Descriptor: | 2-(1H-INDOL-3-YL)ETHANAMINE, D7r4 protein | Authors: | Andersen, J.F, Mans, B.J, Calvo, E, Ribeiro, J.M. | Deposit date: | 2007-05-02 | Release date: | 2007-10-09 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Crystal Structure of D7r4, a Salivary Biogenic Amine-binding Protein from the Malaria Mosquito Anopheles gambiae. J.Biol.Chem., 282, 2007
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2PFQ
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![BU of 2pfq by Molmil](/molmil-images/mine/2pfq) | Manganese promotes catalysis in a DNA polymerase lambda-DNA crystal | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ... | Authors: | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. | Deposit date: | 2007-04-05 | Release date: | 2007-05-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
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1UVJ
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![BU of 1uvj by Molmil](/molmil-images/mine/1uvj) | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 7nt RNA | Descriptor: | 5'-R(*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | Authors: | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | Deposit date: | 2004-01-21 | Release date: | 2004-02-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
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