7BU0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bu0 by Molmil](/molmil-images/mine/7bu0) | |
7WZ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wz5 by Molmil](/molmil-images/mine/7wz5) | Larimichthys crocea IFNi | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon C | Authors: | Chen, J.J. | Deposit date: | 2022-02-17 | Release date: | 2023-02-08 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Molecular and Structural Basis of Receptor Binding and Signaling of a Fish Type I IFN with Three Disulfide Bonds. J Immunol., 209, 2022
|
|
6IV9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6iv9 by Molmil](/molmil-images/mine/6iv9) | the Cas13d binary complex | Descriptor: | Cas13d, MAGNESIUM ION, crRNA (50-MER) | Authors: | Zhang, B, Ye, Y.M, Ye, W.W, OuYang, S.Y. | Deposit date: | 2018-12-02 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d. Nat Commun, 10, 2019
|
|
7BXO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bxo by Molmil](/molmil-images/mine/7bxo) | Crystal structure of the toxin-antitoxin with AMP-PNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Toxin-antitoxin system antidote Mnt family, ... | Authors: | Ouyang, S.Y, Zhen, X.K. | Deposit date: | 2020-04-20 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
|
|
6IV8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6iv8 by Molmil](/molmil-images/mine/6iv8) | the selenomethionine(SeMet)-derived Cas13d binary complex | Descriptor: | MAGNESIUM ION, RNA (51-MER), RNA (53-MER), ... | Authors: | Zhang, B, Ye, Y.M, Ye, W.W, OuYang, S.Y. | Deposit date: | 2018-12-02 | Release date: | 2019-06-19 | Last modified: | 2019-06-26 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d. Nat Commun, 10, 2019
|
|
6DIG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dig by Molmil](/molmil-images/mine/6dig) | Crystal structure of DQA1*01:02/DQB1*06:02 in complex with a hypocretin peptide | Descriptor: | 13-mer peptide: ALA-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-LEU-GLY-LYS, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Birtley, J.R, Stern, L.J, Mellins, E.D, Jiang, W. | Deposit date: | 2018-05-23 | Release date: | 2019-05-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | In vivo clonal expansion and phenotypes of hypocretin-specific CD4+T cells in narcolepsy patients and controls. Nat Commun, 10, 2019
|
|
8I16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i16 by Molmil](/molmil-images/mine/8i16) | Crystal structure of the selenomethionine (SeMet)-derived Cas12g (D513A) mutant | Descriptor: | Cas12g, ZINC ION | Authors: | Zhang, B, Chen, J, Ye, Y.M, OuYang, S.Y. | Deposit date: | 2023-01-12 | Release date: | 2023-08-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural transitions upon guide RNA binding and their importance in Cas12g-mediated RNA cleavage. Plos Genet., 19, 2023
|
|
8I3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i3q by Molmil](/molmil-images/mine/8i3q) | |
4PW8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pw8 by Molmil](/molmil-images/mine/4pw8) | Human tryptophan 2,3-dioxygenase | Descriptor: | COBALT (II) ION, Tryptophan 2,3-dioxygenase | Authors: | Meng, B, Wu, D, Gu, J.H, Ouyang, S.Y, Ding, W, Liu, Z.J. | Deposit date: | 2014-03-19 | Release date: | 2014-08-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.902 Å) | Cite: | Structural and functional analyses of human tryptophan 2,3-dioxygenase Proteins, 82, 2014
|
|
7XVG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xvg by Molmil](/molmil-images/mine/7xvg) | Cryo-EM structure of binary complex of plant NLR Sr35 and effector AvrSr35 | Descriptor: | AvrSr35, Sr35 | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | Deposit date: | 2022-05-23 | Release date: | 2022-09-28 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism. Sci Adv, 8, 2022
|
|
7XX2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xx2 by Molmil](/molmil-images/mine/7xx2) | Cryo-EM structure of Sr35 resistosome induced by AvrSr35 R381A | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, AvrSr35, CNL9 | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | Deposit date: | 2022-05-28 | Release date: | 2022-11-02 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism. Sci Adv, 8, 2022
|
|
7YG3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yg3 by Molmil](/molmil-images/mine/7yg3) | Crystal structure of HLA-B*13:01 | Descriptor: | ARG-GLN-ASP-ILE-LEU-ASP-LEU-TRP-ILE, Beta-2-microglobulin, MHC class I antigen | Authors: | Wang, H.S, Ouyang, S.Y. | Deposit date: | 2022-07-11 | Release date: | 2023-07-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity. J.Biomed.Sci., 29, 2022
|
|
7VKB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vkb by Molmil](/molmil-images/mine/7vkb) | Crystal structure of the a bacterial kinase complex | Descriptor: | DI(HYDROXYETHYL)ETHER, HipA (Persistence to inhibition of murein or DNA biosynthesis), HipA_C domain-containing protein, ... | Authors: | Zhen, X, Ouyang, S.Y. | Deposit date: | 2021-09-29 | Release date: | 2022-06-29 | Last modified: | 2022-08-03 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun, 13, 2022
|
|
7VKC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vkc by Molmil](/molmil-images/mine/7vkc) | Crystal structure of a bacterial Ser/Thr kinase | Descriptor: | HipA_C domain-containing protein | Authors: | Zhen, X, Ouyang, S.Y. | Deposit date: | 2021-09-29 | Release date: | 2022-06-29 | Last modified: | 2022-08-03 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun, 13, 2022
|
|
7WCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wcf by Molmil](/molmil-images/mine/7wcf) | Crystal structure of the kinase with AMP-PNP | Descriptor: | HipA_C domain-containing protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | Authors: | Ouyang, S.Y, Zhen, X. | Deposit date: | 2021-12-20 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.3636 Å) | Cite: | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun, 13, 2022
|
|
7W54
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w54 by Molmil](/molmil-images/mine/7w54) | Crystal structure of a bacterial OTU DUB with Ub-PA | Descriptor: | Lpg2248, Polyubiquitin-B, prop-2-en-1-amine | Authors: | Zhen, X, Ouyang, S.Y. | Deposit date: | 2021-11-29 | Release date: | 2022-08-24 | Last modified: | 2023-04-05 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Structural basis for the dual catalytic activity of the Legionella pneumophila ovarian tumor (OTU) domain deubiquitinase LotA. J.Biol.Chem., 298, 2022
|
|
7VYX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vyx by Molmil](/molmil-images/mine/7vyx) | Crystal structure of the selenomethionine(SeMet)-derived Cas12c1 (D969A) ternary complex | Descriptor: | Non-target DNA strand, Selenomethionine (SeMet)-labeled Cas12c1 D969A mutant, Target DNA strand, ... | Authors: | Zhang, B, Lin, J.Y, Perculija, V, OuYang, S.Y. | Deposit date: | 2021-11-15 | Release date: | 2022-11-02 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system Nucleic Acids Res., 50, 2022
|
|
7XE0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xe0 by Molmil](/molmil-images/mine/7xe0) | Cryo-EM structure of plant NLR Sr35 resistosome | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, AvrSr35, Sr35 | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | Deposit date: | 2022-03-29 | Release date: | 2022-09-28 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism. Sci Adv, 8, 2022
|
|
6K4R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k4r by Molmil](/molmil-images/mine/6k4r) | |
6K4K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k4k by Molmil](/molmil-images/mine/6k4k) | |
6KS5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ks5 by Molmil](/molmil-images/mine/6ks5) | |
6IM4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6im4 by Molmil](/molmil-images/mine/6im4) | |
6IST
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ist by Molmil](/molmil-images/mine/6ist) | Crystal structure of a wild type endolysin LysIME-EF1 | Descriptor: | CALCIUM ION, Lysin | Authors: | Ouyang, S.Y. | Deposit date: | 2018-11-19 | Release date: | 2019-11-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and functional insights into a novel two-component endolysin encoded by a single gene in Enterococcus faecalis phage. Plos Pathog., 16, 2020
|
|
6L00
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l00 by Molmil](/molmil-images/mine/6l00) | |
6JKY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jky by Molmil](/molmil-images/mine/6jky) | |