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4GSB
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BU of 4gsb by Molmil
Monoclinic crystal form of the apo-ERK2
Descriptor: GLYCEROL, Mitogen-activated protein kinase 1, SULFATE ION, ...
Authors:Pozharski, E, Zhang, J, Shapiro, P.
Deposit date:2012-08-27
Release date:2012-09-12
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Monoclinic crystal form of the apo-ERK2
TO BE PUBLISHED
3MCI
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BU of 3mci by Molmil
Crystal structure of molybdenum cofactor biosynthesis (AQ_061) from aquifex aeolicus VF5
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Molybdenum cofactor biosynthesis MOG
Authors:Jeyakanthan, J, Kanaujia, S.P, Sekar, K, Agari, Y, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2010-03-29
Release date:2011-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures, dynamics and functional implications of molybdenum-cofactor biosynthesis protein MogA from two thermophilic organisms
Acta Crystallogr.,Sect.F, 67, 2011
3SLP
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BU of 3slp by Molmil
Crystal Structure of Lambda Exonuclease in Complex with a 12 BP Symmetric DNA Duplex
Descriptor: 5'-D(*GP*CP*GP*AP*CP*TP*AP*GP*TP*CP*GP*C)-3', CALCIUM ION, CHLORIDE ION, ...
Authors:Bell, C.E, Zhang, J.
Deposit date:2011-06-24
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SM4
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BU of 3sm4 by Molmil
Crystal Structure of the K131A Mutant of Lambda Exonuclease in Complex with a 5'-Phosphorylated 14-mer/12-mer Duplex and Magnesium
Descriptor: 5'-D(*TP*CP*GP*GP*TP*AP*CP*AP*GP*TP*AP*G)-3', 5'-D(P*AP*GP*CP*TP*AP*CP*TP*GP*TP*AP*CP*CP*GP*A)-3', CHLORIDE ION, ...
Authors:Bell, C.E, Zhang, J.
Deposit date:2011-06-27
Release date:2011-07-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
Proc.Natl.Acad.Sci.USA, 108, 2011
3VHZ
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BU of 3vhz by Molmil
Crystal structure of the trans isomer of the L93A mutant of bacteriorhodopsin
Descriptor: 2,3-DI-PHYTANYL-GLYCEROL, 3-O-sulfo-beta-D-galactopyranose-(1-6)-alpha-D-mannopyranose-(1-2)-alpha-D-glucopyranose, Bacteriorhodopsin, ...
Authors:Kouyama, T, Zhang, J.
Deposit date:2011-09-13
Release date:2012-06-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the O intermediate of the Leu93Ala mutant of bacteriorhodopsin
Proteins, 80, 2012
3VI0
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BU of 3vi0 by Molmil
Crystal structure of the O intermediate of the L93A mutant of bacteriorhodopsin
Descriptor: 2,3-DI-PHYTANYL-GLYCEROL, 3-O-sulfo-beta-D-galactopyranose-(1-6)-alpha-D-mannopyranose-(1-2)-alpha-D-glucopyranose, Bacteriorhodopsin, ...
Authors:Kouyama, T, Zhang, J.
Deposit date:2011-09-13
Release date:2012-06-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the O intermediate of the Leu93Ala mutant of bacteriorhodopsin
Proteins, 80, 2012
4JMO
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BU of 4jmo by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-14
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
4JXH
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BU of 4jxh by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH 8.5
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide, PHOSPHATE ION
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-28
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
4JMI
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BU of 4jmi by Molmil
Sec7 domain of ARNO, an exchange factor, at 1.5 Angstrom resolution
Descriptor: Cytohesin-2
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-14
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
4L5M
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BU of 4l5m by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH6.5
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide, PHOSPHATE ION
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-06-11
Release date:2013-10-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors.
J.Med.Chem., 56, 2013
4JWL
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BU of 4jwl by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH7.5
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-27
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
4L9H
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BU of 4l9h by Molmil
Crystal structure of the FP domain of human F-box protein Fbxo7(SeMet)
Descriptor: F-box only protein 7
Authors:Du, Z, Huang, X, Shang, J, Yang, Y, Wang, G.
Deposit date:2013-06-18
Release date:2014-01-15
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the FP domain of Fbxo7 reveals a novel mode of protein-protein interaction.
Acta Crystallogr.,Sect.D, 70, 2014
4L9C
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BU of 4l9c by Molmil
Crystal structure of the FP domain of human F-box protein Fbxo7 (native)
Descriptor: F-box only protein 7, GLYCEROL
Authors:Du, Z, Huang, X, Shang, J, Yang, Y, Wang, G.
Deposit date:2013-06-18
Release date:2014-01-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the FP domain of Fbxo7 reveals a novel mode of protein-protein interaction.
Acta Crystallogr.,Sect.D, 70, 2014
4MSU
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BU of 4msu by Molmil
Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate
Descriptor: 1,1,1,3,3,3-hexafluoro-2-{4-[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ...
Authors:Ashton, K.S, Andrews, K.L, Bryan, M.C, Chen, J, Chen, K, Chen, M, Chmait, S, Croghan, M, Cupples, R, Fotsch, C, Helmering, J, Jordan, S.R, Kurzeja, R.J, Michelsen, K, Pennington, L.D, Poon, S.F, Sivits, G, Van, G, Vonderfecht, S.L, Wahl, R.C, Zhang, J, Lloyd, D.J, Hale, C, St Jean, D.J.
Deposit date:2013-09-18
Release date:2014-03-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept.
J.Med.Chem., 57, 2014
4URT
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BU of 4urt by Molmil
The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Finci, L.I, Krueger, N, Sun, X, Zhang, J, Chegkazi, M, Wu, Y, Schenk, G, Mertens, H.D.T, Svergun, D.I, Zhang, Y, Wang, J.-h, Meijers, R.
Deposit date:2014-07-02
Release date:2014-09-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Crystal Structure of Netrin-1 in Complex with Dcc Reveals the Bi-Functionality of Netrin-1 as a Guidance Cue
Neuron, 83, 2014
5MLB
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BU of 5mlb by Molmil
Crystal structure of human RAS in complex with darpin K27
Descriptor: DARPin K27, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Debreczeni, J.E, Guillard, S, Kolasinska-Zwierz, P, Breed, J, Zhang, J, Bery, N, Marwood, R, Tart, J, Overman, R, Stocki, P, Mistry, B, Phillips, C, Rabbitts, T, Jackson, R, Minter, R.
Deposit date:2016-12-06
Release date:2017-12-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:INhibition of RAS nucleotide exchange by a DARPin: structural characterisation and effects on downstream signalling by active RAS
To Be Published
7O1N
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BU of 7o1n by Molmil
Crystal Structure of Human Neuropilin-1 b1 Domain mutant - Y297A
Descriptor: Neuropilin-1
Authors:Djordjevic, S, Chandanani, J, Faleeva, M, Pinotsis, N.
Deposit date:2021-03-29
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Crystal Structure of Human Neuropilin-1 b1 Domain mutant - Y297A
To Be Published
6C5W
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BU of 6c5w by Molmil
Crystal structure of the mitochondrial calcium uniporter
Descriptor: CALCIUM ION, calcium uniporter, nanobody
Authors:Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L.
Deposit date:2018-01-17
Release date:2018-07-11
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.10010242 Å)
Cite:X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
Nature, 559, 2018
4M00
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BU of 4m00 by Molmil
Crystal structure of the ligand binding region of staphylococcal adhesion SraP
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Serine-rich adhesin for platelets, ...
Authors:Yang, Y.H, Jiang, Y.L, Zhang, J, Wang, L, Chen, Y, Zhou, C.Z.
Deposit date:2013-08-01
Release date:2014-06-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Insights into SraP-Mediated Staphylococcus aureus Adhesion to Host Cells
Plos Pathog., 10, 2014
3ZDA
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BU of 3zda by Molmil
Structure of E. coli ExoIX in complex with a fragment of the Flap1 DNA oligonucleotide, potassium and magnesium
Descriptor: 5'-D(*AP*AP*GP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*CP)-3', MAGNESIUM ION, ...
Authors:Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J.
Deposit date:2012-11-26
Release date:2013-07-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
7F42
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BU of 7f42 by Molmil
PARP15 catalytic domain in complex with Iniparib
Descriptor: 4-iodo-3-nitrobenzamide, Protein mono-ADP-ribosyltransferase PARP15
Authors:Zhou, X.L, Zhou, H, Li, J, Zhang, J.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:PARP15 catalytic domain in complex with Iniparib
To Be Published
7F41
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BU of 7f41 by Molmil
PARP15 catalytic domain in complex with 3-AMINOBENZAMIDE
Descriptor: 3-aminobenzamide, Protein mono-ADP-ribosyltransferase PARP15
Authors:Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.39721382 Å)
Cite:PARP15 catalytic domain in complex with 3-AMINOBENZAMIDE
To Be Published
7F43
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BU of 7f43 by Molmil
PARP15 catalytic domain in complex with Niraparib
Descriptor: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, Protein mono-ADP-ribosyltransferase PARP15
Authors:Zhou, X.L, Zhou, H, Li, J, Zhang, J.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:PARP15 catalytic domain in complex with Niraparib
To Be Published
3ZD9
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BU of 3zd9 by Molmil
Potassium bound structure of E. coli ExoIX in P21
Descriptor: POTASSIUM ION, PROTEIN XNI
Authors:Anstey-Gilbert, C.S, Hemsworth, G.R, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J.
Deposit date:2012-11-26
Release date:2013-07-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
5XJX
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BU of 5xjx by Molmil
Pre-formed plant receptor ERL1-TMM complex
Descriptor: LRR receptor-like serine/threonine-protein kinase ERL1, Protein TOO MANY MOUTHS
Authors:Chai, J, Lin, G, Zhang, L, Han, Z, Yang, X, Liu, W, Qi, Y, Chang, J, Li, E.
Deposit date:2017-05-04
Release date:2019-01-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.055 Å)
Cite:A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017

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