1CPY
| SITE-DIRECTED MUTAGENESIS ON (SERINE) CARBOXYPEPTIDASE Y FROM YEAST. THE SIGNIFICANCE OF THR 60 AND MET 398 IN HYDROLYSIS AND AMINOLYSIS REACTIONS | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SERINE CARBOXYPEPTIDASE | Authors: | Sorensen, S.B, Raaschou-Nielsen, M, Mortensen, U, Remington, S.J, Breddam, K. | Deposit date: | 1995-03-24 | Release date: | 1995-09-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Site-Directed Mutagenesis on (Serine) Carboxypeptidase Y from Yeast. The Significance of Thr 60 and met 398 in Hydrolysis and Aminolysis Reactions J.Am.Chem.Soc., 117, 1995
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1DD8
| CRYSTAL STRUCTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE I FROM ESCHERICHIA COLI | Descriptor: | BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I | Authors: | Olsen, J.G, Kadziola, A, von Wettstein-Knowles, P, Siggaard-Andersen, M, Lindquist, Y, Larsen, S. | Deposit date: | 1999-11-09 | Release date: | 1999-11-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I. FEBS Lett., 460, 1999
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3BFU
| Structure of the ligand-binding core of GluR2 in complex with the agonist (R)-TDPA at 1.95 A resolution | Descriptor: | (2R)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid, Glutamate receptor 2 | Authors: | Beich-Frandsen, M, Mirza, O, Vestergaard, B, Gajhede, M, Kastrup, J.S. | Deposit date: | 2007-11-23 | Release date: | 2008-10-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. J.Med.Chem., 51, 2008
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1BL1
| PTH RECEPTOR N-TERMINUS FRAGMENT, NMR, 1 STRUCTURE | Descriptor: | PARATHYROID HORMONE RECEPTOR | Authors: | Pellegrini, M, Bisello, A, Rosenblatt, M, Chorev, M, Mierke, D.F. | Deposit date: | 1998-07-22 | Release date: | 1999-03-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Binding domain of human parathyroid hormone receptor: from conformation to function. Biochemistry, 37, 1998
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1F91
| BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I IN COMPLEX WITH C10 FATTY ACID SUBSTRATE | Descriptor: | BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, DECANOIC ACID, HYDROXIDE ION | Authors: | Olsen, J.G, Kadziola, A, Wettstein-Knowles, P.V, Siggaard-Andersen, M, Larsen, S. | Deposit date: | 2000-07-06 | Release date: | 2001-04-11 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery. Structure, 9, 2001
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1TXT
| Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase | Descriptor: | 3-hydroxy-3-methylglutaryl-CoA synthase, ACETOACETYL-COENZYME A | Authors: | Campobasso, N, Patel, M, Wilding, I.E, Kallender, H, Rosenberg, M, Gwynn, M. | Deposit date: | 2004-07-06 | Release date: | 2004-08-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism J.Biol.Chem., 279, 2004
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1TVZ
| Crystal structure of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Staphylococcus aureus | Descriptor: | 3-hydroxy-3-methylglutaryl-CoA synthase, SULFATE ION | Authors: | Campobasso, N, Patel, M, Wilding, I.E, Kallender, H, Rosenberg, M, Gwynn, M. | Deposit date: | 2004-06-30 | Release date: | 2004-08-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism J.Biol.Chem., 279, 2004
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4AF2
| C61S mutant of thiol peroxidase form E. coli. | Descriptor: | THIOL PEROXIDASE | Authors: | Beckham, K.S.H, Roe, A.J, Byron, O, Gabrielsen, M. | Deposit date: | 2012-01-16 | Release date: | 2012-05-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | The Structure of an Orthorhombic Crystal Form of a `Forced Reduced' Thiol Peroxidase Reveals Lattice Formation Aided by the Presence of the Affinity Tag Acta Crystallogr.,Sect.F, 68, 2012
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4AXP
| NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast. | Descriptor: | 12 KDA HEAT SHOCK PROTEIN | Authors: | Herbert, A.P, Riesen, M, Bloxam, L, Kosmidou, E, Wareing, B.M, Johnson, J.R, Phelan, M.M, Pennington, S.R, Lian, L.Y, Morgan, A. | Deposit date: | 2012-06-13 | Release date: | 2012-08-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Structure of Hsp12, a Protein Induced by and Required for Dietary Restriction-Induced Lifespan Extension in Yeast. Plos One, 7, 2012
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1PLG
| EVIDENCE FOR THE EXTENDED HELICAL NATURE OF POLYSACCHARIDE EPITOPES. THE 2.8 ANGSTROMS RESOLUTION STRUCTURE AND THERMODYNAMICS OF LIGAND BINDING OF AN ANTIGEN BINDING FRAGMENT SPECIFIC FOR ALPHA-(2->8)-POLYSIALIC ACID | Descriptor: | IGG2A=KAPPA= | Authors: | Evans, S.V, Sigurskjold, B.W, Jennings, H.J, Brisson, J.-R, Tse, W.C, To, R, Altman, E, Frosch, M, Weisgerber, C, Kratzin, H, Klebert, S, Vaesen, M, Bitter-Suermann, D, Rose, D.R, Young, N.M, Bundle, D.R. | Deposit date: | 1995-04-24 | Release date: | 1996-04-03 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2-->8)-polysialic acid. Biochemistry, 34, 1995
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1RNF
| X-RAY CRYSTAL STRUCTURE OF UNLIGANDED HUMAN RIBONUCLEASE 4 | Descriptor: | PROTEIN (RIBONUCLEASE 4) | Authors: | Terzyan, S.S, Peracaula, R, De Llorens, R, Tsushima, Y, Yamada, H, Seno, M, Gomis-Rueth, F.X, Coll, M. | Deposit date: | 1998-10-29 | Release date: | 1999-10-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The three-dimensional structure of human RNase 4, unliganded and complexed with d(Up), reveals the basis for its uridine selectivity. J.Mol.Biol., 285, 1999
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1B6Y
| 3,N4-ETHENO-2'-DEOXYCYTIDINE OPPOSITE ADENINE IN AN 11-MER DUPLEX, SOLUTION STRUCTURE FROM NMR AND MOLECULAR DYNAMICS, 2 STRUCTURES | Descriptor: | 5'-D(*CP*GP*TP*AP*CP*(EDC)P*CP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*GP*AP*GP*TP*AP*CP*G)-3' | Authors: | Korobka, A, Cullinan, D, Cosman, M, Grollman, A.P, Patel, D.J, Eisenberg, M, De Los Santos, C. | Deposit date: | 1999-01-19 | Release date: | 1999-01-27 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | Solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite 2'-deoxyadenosine, determined by NMR spectroscopy and restrained molecular dynamics. Biochemistry, 35, 1996
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1DYT
| X-ray crystal structure of ECP (RNase 3) at 1.75 A | Descriptor: | CITRIC ACID, EOSINOPHIL CATIONIC PROTEIN, FE (III) ION | Authors: | Mallorqui-Fernandez, G, Pous, J, Peracaula, R, Maeda, T, Tada, H, Yamada, H, Seno, M, De Llorens, R, Gomis-Rueth, F.X, Coll, M. | Deposit date: | 2000-02-08 | Release date: | 2001-02-08 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Three-Dimensional Crystal Structure of Human Eosinophil Cationic Protein (Rnase 3) at 1.75 A Resolution. J.Mol.Biol., 300, 2000
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3WRB
| Crystal structure of the anaerobic H124F DESb-Gallate complex | Descriptor: | 3,4,5-trihydroxybenzoic acid, FE (II) ION, Gallate dioxygenase | Authors: | Sugimoto, K, Senda, M, Kasai, D, Fukuda, M, Masai, E, Senda, T. | Deposit date: | 2014-02-21 | Release date: | 2014-04-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6 Plos One, 9, 2014
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3WRC
| Crystal structure of the anaerobic DesB-Protocatechuate (PCA) complex | Descriptor: | 3,4-DIHYDROXYBENZOIC ACID, FE (II) ION, Gallate dioxygenase | Authors: | Sugimoto, K, Senda, M, Kasai, D, Fukuda, M, Masai, E, Senda, T. | Deposit date: | 2014-02-21 | Release date: | 2014-04-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6 Plos One, 9, 2014
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3WPM
| Crystal structure of the anaerobic DesB-gallate complex by co-crystallization | Descriptor: | 3,4,5-trihydroxybenzoic acid, FE (III) ION, Gallate dioxygenase | Authors: | Sugimoto, K, Senda, M, Kasai, D, Fukuda, M, Masai, E, Senda, T. | Deposit date: | 2014-01-14 | Release date: | 2014-04-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6 Plos One, 9, 2014
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3WR4
| Crystal structure of the anaerobic DesB-gallate complex | Descriptor: | 3,4,5-trihydroxybenzoic acid, FE (III) ION, Gallate dioxygenase | Authors: | Sugimoto, K, Senda, M, Kasai, D, Fukuda, M, Masai, E, Senda, T. | Deposit date: | 2014-02-13 | Release date: | 2014-04-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6 Plos One, 9, 2014
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3WRA
| Crystal structure of the desB-Gallate complex exposed to Aerobic Atomosphere | Descriptor: | FE (II) ION, Gallate dioxygenase | Authors: | Sugimoto, K, Senda, M, Kasai, D, Fukuda, M, Masai, E, Senda, T. | Deposit date: | 2014-02-21 | Release date: | 2014-04-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6 Plos One, 9, 2014
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3WR3
| Crystal structure of the anaerobic DesB-gallate complex | Descriptor: | 3,4,5-trihydroxybenzoic acid, FE (II) ION, Gallate dioxygenase | Authors: | Sugimoto, K, Senda, M, Kasai, D, Fukuda, M, Masai, E, Senda, T. | Deposit date: | 2014-02-13 | Release date: | 2014-04-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6 Plos One, 9, 2014
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3WKU
| Crystal structure of the anaerobic DesB-gallate complex | Descriptor: | 3,4,5-trihydroxybenzoic acid, FE (III) ION, Gallate dioxygenase | Authors: | Sugimoto, K, Senda, M, Kasai, D, Fukuda, M, Masai, E, Senda, T. | Deposit date: | 2013-10-31 | Release date: | 2014-04-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6 Plos One, 9, 2014
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3WR8
| Crystal structure of DesB from Sphingobium sp. strain SYK-6 | Descriptor: | FE (II) ION, Gallate dioxygenase | Authors: | Sugimoto, K, Senda, M, Kasai, D, Fukuda, M, Masai, E, Senda, T. | Deposit date: | 2014-02-21 | Release date: | 2014-04-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6 Plos One, 9, 2014
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1E21
| Ribonuclease 1 des1-7 Crystal Structure at 1.9A | Descriptor: | RIBONUCLEASE 1 | Authors: | Pous, J, Mallorqui-Fernandez, G, Peracaula, R, Terzyan, S.S, Futami, J, Tada, H, Yamada, H, Seno, M, De Llorens, R, Gomis-Ruth, F.X, Coll, M. | Deposit date: | 2000-05-15 | Release date: | 2001-05-03 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Three-Dimensional Crystal Structure of Human Rnase 1Dn7 at 1.9A Resolution Acta Crystallogr.,Sect.D, 57, 2001
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3X06
| Crystal structure of PIP4KIIBETA T201M complex with GMP | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T. | Deposit date: | 2014-10-09 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61, 2016
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3X05
| Crystal structure of PIP4KIIBETA T201M complex with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T. | Deposit date: | 2014-10-09 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61, 2016
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3X03
| Crystal structure of PIP4KIIBETA complex with AMPPNP | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T. | Deposit date: | 2014-10-09 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61, 2016
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