5HJC
| BRD3 second bromodomain in complex with histone H3 acetylation at K18 | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 3, CHLORIDE ION, ... | Authors: | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | Deposit date: | 2016-01-13 | Release date: | 2016-04-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain Mol.Cell, 62, 2016
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5TBM
| Crystal structure of PT2385 bound to HIF2a-B*:ARNT-B* complex | Descriptor: | 3-{[(1S)-2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | Authors: | Du, X. | Deposit date: | 2016-09-12 | Release date: | 2016-09-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A Small-Molecule Antagonist of HIF2 alpha Is Efficacious in Preclinical Models of Renal Cell Carcinoma. Cancer Res., 76, 2016
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