8STH
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![BU of 8sth by Molmil](/molmil-images/mine/8sth) | human STING with diABZI agonist 15 | Descriptor: | 1-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazole-5-carboxamide, Stimulator of interferon genes protein | Authors: | Duvall, J.R, Bukhalid, R.A. | Deposit date: | 2023-05-10 | Release date: | 2023-07-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates. J.Med.Chem., 66, 2023
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8SA2
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![BU of 8sa2 by Molmil](/molmil-images/mine/8sa2) | Adenosylcobalamin-bound riboswitch dimer, form 1 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 1 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SA4
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![BU of 8sa4 by Molmil](/molmil-images/mine/8sa4) | Adenosylcobalamin-bound riboswitch dimer, form 3 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 3 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SSU
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![BU of 8ssu by Molmil](/molmil-images/mine/8ssu) | ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 19mer DNA | Descriptor: | 1,2-ETHANEDIOL, DNA (19-MER) Strand I, DNA (19-MER) Strand II, ... | Authors: | Horton, J.R, Yang, J, Cheng, X. | Deposit date: | 2023-05-08 | Release date: | 2023-08-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Structures of CTCF-DNA complexes including all 11 zinc fingers. Nucleic Acids Res., 51, 2023
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8SST
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![BU of 8sst by Molmil](/molmil-images/mine/8sst) | ZnFs 1-7 of CCCTC-binding factor (CTCF) K365T Mutant Complexed with 23mer | Descriptor: | 1,2-ETHANEDIOL, DNA Strand (23mer) I, DNA Strand (23mer) II, ... | Authors: | Horton, J.R, Yang, J, Cheng, X. | Deposit date: | 2023-05-08 | Release date: | 2023-08-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structures of CTCF-DNA complexes including all 11 zinc fingers. Nucleic Acids Res., 51, 2023
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8SA3
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![BU of 8sa3 by Molmil](/molmil-images/mine/8sa3) | Adenosylcobalamin-bound riboswitch dimer, form 2 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 2 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8S9M
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![BU of 8s9m by Molmil](/molmil-images/mine/8s9m) | DNA cytosine-N4 methyltransferase (residues 79-324) from the Bdelloid rotifer Adineta vaga | Descriptor: | 1,2-ETHANEDIOL, DNA cytosine-N4 methyltransferase, SINEFUNGIN | Authors: | Zhou, J, Horton, J.R, Cheng, X. | Deposit date: | 2023-03-29 | Release date: | 2023-08-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga. J.Biol.Chem., 299, 2023
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8SA6
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![BU of 8sa6 by Molmil](/molmil-images/mine/8sa6) | apo form of adenosylcobalamin riboswitch dimer | Descriptor: | apo form of adenosylcobalamin riboswitch dimer | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (5.3 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SA5
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![BU of 8sa5 by Molmil](/molmil-images/mine/8sa5) | Adenosylcobalamin-bound riboswitch dimer, form 4 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 4 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SSS
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![BU of 8sss by Molmil](/molmil-images/mine/8sss) | ZnFs 1-7 of CCCTC-binding factor (CTCF) Complexed with 23mer | Descriptor: | 1,2-ETHANEDIOL, DNA Strand (23mer) I, DNA Strand (23mer) II, ... | Authors: | Horton, J.R, Yang, J, Cheng, X. | Deposit date: | 2023-05-08 | Release date: | 2023-08-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of CTCF-DNA complexes including all 11 zinc fingers. Nucleic Acids Res., 51, 2023
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8STI
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![BU of 8sti by Molmil](/molmil-images/mine/8sti) | human STING with agonist XMT-1616 | Descriptor: | 3-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-3H-imidazo[4,5-b]pyridine-6-carboxamide, Stimulator of interferon genes protein | Authors: | Duvall, J.R, Bukhalid, R.A. | Deposit date: | 2023-05-10 | Release date: | 2023-07-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates. J.Med.Chem., 66, 2023
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8S9N
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![BU of 8s9n by Molmil](/molmil-images/mine/8s9n) | DNA cytosine-N4 methyltransferase (residues 61-324) from the Bdelloid rotifer Adineta vaga - C2 crystal form | Descriptor: | 1,2-ETHANEDIOL, DNA cytosine-N4 methyltransferase, SINEFUNGIN | Authors: | Zhou, J, Horton, J.R, Cheng, X. | Deposit date: | 2023-03-29 | Release date: | 2023-08-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga. J.Biol.Chem., 299, 2023
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8SSQ
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![BU of 8ssq by Molmil](/molmil-images/mine/8ssq) | ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 35mer DNA 35-4 | Descriptor: | DNA (35-MER) Strand 2, DNA (35-MER) Strand I, SODIUM ION, ... | Authors: | Horton, J.R, Yang, J, Cheng, X. | Deposit date: | 2023-05-08 | Release date: | 2023-08-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Structures of CTCF-DNA complexes including all 11 zinc fingers. Nucleic Acids Res., 51, 2023
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8SSR
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![BU of 8ssr by Molmil](/molmil-images/mine/8ssr) | ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 35mer DNA 35-20 | Descriptor: | DNA (35-MER) Strand I, DNA (35-MER) Strand II, SODIUM ION, ... | Authors: | Horton, J.R, Yang, J, Cheng, X. | Deposit date: | 2023-05-08 | Release date: | 2023-08-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | Structures of CTCF-DNA complexes including all 11 zinc fingers. Nucleic Acids Res., 51, 2023
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8S9O
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![BU of 8s9o by Molmil](/molmil-images/mine/8s9o) | DNA cytosine-N4 methyltransferase (residues 61-324) from the Bdelloid rotifer Adineta vaga - P1 crystal form | Descriptor: | 1,2-ETHANEDIOL, DNA cytosine-N4 methyltransferase, SINEFUNGIN | Authors: | Zhou, J, Horton, J.R, Cheng, X. | Deposit date: | 2023-03-29 | Release date: | 2023-08-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga. J.Biol.Chem., 299, 2023
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7YQ2
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![BU of 7yq2 by Molmil](/molmil-images/mine/7yq2) | Crystal structure of photosystem II expressing psbA2 gene only | Descriptor: | (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | Authors: | Nakajima, Y, Suga, M, Shen, J.R. | Deposit date: | 2022-08-05 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of photosystem II from a cyanobacterium expressing psbA 2 in comparison to psbA 3 reveal differences in the D1 subunit. J.Biol.Chem., 298, 2022
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7YQ7
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![BU of 7yq7 by Molmil](/molmil-images/mine/7yq7) | Crystal structure of photosystem II expressing psbA3 gene only | Descriptor: | (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | Authors: | Nakajima, Y, Suga, M, Shen, J.R. | Deposit date: | 2022-08-05 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of photosystem II from a cyanobacterium expressing psbA 2 in comparison to psbA 3 reveal differences in the D1 subunit. J.Biol.Chem., 298, 2022
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7Z5E
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![BU of 7z5e by Molmil](/molmil-images/mine/7z5e) | VP2-only capsid of MVM D263A mutant | Descriptor: | Capsid protein VP1 | Authors: | Luque, D, Ortega-Esteban, A, Valbuena, A, Vilas, J.L, Rodriguez-Huete, A, Mateu, M.G, Caston, J.R. | Deposit date: | 2022-03-09 | Release date: | 2023-03-08 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Equilibrium Dynamics of a Biomolecular Complex Analyzed at Single-amino Acid Resolution by Cryo-electron Microscopy. J.Mol.Biol., 435, 2023
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7Z5F
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![BU of 7z5f by Molmil](/molmil-images/mine/7z5f) | VP2-only capsid of MVM D263A mutant | Descriptor: | Capsid protein VP1 | Authors: | Luque, D, Ortega-Esteban, A, Valbuena, A, Vilas, J.L, Rodriguez-Huete, A, Mateu, M.G, Caston, J.R. | Deposit date: | 2022-03-09 | Release date: | 2023-03-08 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Equilibrium Dynamics of a Biomolecular Complex Analyzed at Single-amino Acid Resolution by Cryo-electron Microscopy. J.Mol.Biol., 435, 2023
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7Z5D
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![BU of 7z5d by Molmil](/molmil-images/mine/7z5d) | VP2-only capsid of wt MVM prototype strain p | Descriptor: | Capsid protein VP1 | Authors: | Luque, D, Ortega-Esteban, A, Valbuena, A, Vilas, J.L, Rodriguez-Huete, A, Mateu, M.G, Caston, J.R. | Deposit date: | 2022-03-09 | Release date: | 2023-03-08 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Equilibrium Dynamics of a Biomolecular Complex Analyzed at Single-amino Acid Resolution by Cryo-electron Microscopy. J.Mol.Biol., 435, 2023
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7ZC7
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![BU of 7zc7 by Molmil](/molmil-images/mine/7zc7) | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012941 | Descriptor: | 2-[4-(3,5-dimethylpyrazol-1-yl)phenyl]-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)ethanamide, N-glycosylase/DNA lyase, NICKEL (II) ION | Authors: | Davies, J.R, Scaletti, E, Stenmark, P. | Deposit date: | 2022-03-25 | Release date: | 2023-07-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012941 To Be Published
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7YMI
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![BU of 7ymi by Molmil](/molmil-images/mine/7ymi) | PSII-Pcb Dimer of Acaryochloris Marina | Descriptor: | (1R,2S)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol, (6'R,11cis,11'cis,13cis,15cis)-4',5'-didehydro-5',6'-dihydro-beta,beta-carotene, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ... | Authors: | Shen, L.L, Gao, Y.Z, Wang, W.D, Zhang, X, Shen, J.R, Wang, P.Y, Han, G.Y. | Deposit date: | 2022-07-28 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of a large photosystem II supercomplex from Acaryochloris marina. To Be Published
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7YMM
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![BU of 7ymm by Molmil](/molmil-images/mine/7ymm) | PSII-Pcb Tetramer of Acaryochloris Marina | Descriptor: | (1R,2S)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol, (6'R,11cis,11'cis,13cis,15cis)-4',5'-didehydro-5',6'-dihydro-beta,beta-carotene, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ... | Authors: | Shen, L.L, Gao, Y.Z, Wang, W.D, Zhang, X, Shen, J.R, Wang, P.Y, Han, G.Y. | Deposit date: | 2022-07-28 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of a large photosystem II supercomplex from Acaryochloris marina. To Be Published
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7ZG3
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![BU of 7zg3 by Molmil](/molmil-images/mine/7zg3) | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH011228 | Descriptor: | N-glycosylase/DNA lyase, NICKEL (II) ION, ~{N}-[(1~{S})-1,2,2-trimethylcyclopropyl]pyrrolo[1,2-c]pyrimidine-3-carboxamide | Authors: | Davies, J.R, Scaletti, E, Stenmark, P. | Deposit date: | 2022-04-01 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH011228 To Be Published
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8A4F
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![BU of 8a4f by Molmil](/molmil-images/mine/8a4f) | Human Interleukin-4 mutant - C3T-IL4 | Descriptor: | Interleukin-4 | Authors: | Vaz, D.C, Rodrigues, J.R, Mueller, T.D, Sebald, W, Redfield, C, Brito, R.M.M. | Deposit date: | 2022-06-11 | Release date: | 2023-10-18 | Last modified: | 2024-01-17 | Method: | SOLUTION NMR | Cite: | Lessons on protein structure from interleukin-4: All disulfides are not created equal. Proteins, 92, 2024
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