3RFE
 
 | | Crystal structure of glycoprotein GPIb ectodomain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Platelet glycoprotein Ib beta chain, ... | | Authors: | McEwan, P.A, Yang, W, Carr, K.H, Mo, X, Zheng, X, Li, R, Emsley, J. | | Deposit date: | 2011-04-06 | | Release date: | 2011-12-21 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.245 Å) | | Cite: | Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbbeta and a GPIbbeta/GPIX chimer
Blood, 118, 2011
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1XDT
 | | COMPLEX OF DIPHTHERIA TOXIN AND HEPARIN-BINDING EPIDERMAL GROWTH FACTOR | | Descriptor: | DIPHTHERIA TOXIN, HEPARIN-BINDING EPIDERMAL GROWTH FACTOR | | Authors: | Louie, G.V, Yang, W, Bowman, M.E, Choe, S. | | Deposit date: | 1997-11-18 | | Release date: | 1998-02-25 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor.
Mol.Cell, 1, 1997
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7KQN
 | | Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex | | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | Authors: | Choi, W.S, Weng, P.J, Yang, W. | | Deposit date: | 2020-11-17 | | Release date: | 2022-03-23 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Flexibility of telomerase in binding the RNA template and DNA telomeric repeat.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7KQM
 | | Binary complex of TERT (telomerase reverse transcriptase) with RNA/telomeric DNA hybrid | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*GP*CP*AP*CP*CP*TP*G)-3'), ... | | Authors: | Choi, W.S, Weng, P.J, Yang, W. | | Deposit date: | 2020-11-17 | | Release date: | 2022-03-23 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | Flexibility of telomerase in binding the RNA template and DNA telomeric repeat.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1YQK
 | | Human 8-oxoguanine glycosylase crosslinked with guanine containing DNA | | Descriptor: | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*G)-3', 5'-D(P*CP*AP*GP*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... | | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | | Deposit date: | 2005-02-01 | | Release date: | 2005-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.
Nature, 434, 2005
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1YQR
 | | Catalytically inactive human 8-oxoguanine glycosylase crosslinked to oxoG containing DNA | | Descriptor: | 5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', CALCIUM ION, ... | | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | | Deposit date: | 2005-02-02 | | Release date: | 2005-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.
Nature, 434, 2005
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1YQL
 | | Catalytically inactive hOGG1 crosslinked with 7-deaza-8-azaguanine containing DNA | | Descriptor: | 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*CP*AP*(PPW)P*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... | | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | | Deposit date: | 2005-02-02 | | Release date: | 2005-04-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.
Nature, 434, 2005
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1YQM
 | | Catalytically inactive human 8-oxoguanine glycosylase crosslinked to 7-deazaguanine containing DNA | | Descriptor: | 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*CP*AP*(7GU)P*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... | | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | | Deposit date: | 2005-02-02 | | Release date: | 2005-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.
Nature, 434, 2005
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1XRX
 | | Crystal structure of a DNA-binding protein | | Descriptor: | CALCIUM ION, SeqA protein | | Authors: | Guarne, A, Brendler, T, Zhao, Q, Ghirlando, R, Austin, S, Yang, W. | | Deposit date: | 2004-10-16 | | Release date: | 2005-05-10 | | Last modified: | 2013-03-06 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structure of a SeqA-N filament: implications for DNA replication and chromosome organization.
Embo J., 24, 2005
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1ZBL
 | | Bacillus halodurans RNase H catalytic domain mutant D192N in complex with 12-mer RNA/DNA hybrid | | Descriptor: | 5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3', 5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3', MAGNESIUM ION, ... | | Authors: | Nowotny, M, Gaidamakov, S.A, Crouch, R.J, Yang, W. | | Deposit date: | 2005-04-08 | | Release date: | 2005-07-12 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Cell(Cambridge,Mass.), 121, 2005
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1X9Z
 | | Crystal structure of the MutL C-terminal domain | | Descriptor: | CHLORIDE ION, DNA mismatch repair protein mutL, GLYCEROL, ... | | Authors: | Guarne, A, Ramon-Maiques, S, Wolff, E.M, Ghirlando, R, Hu, X, Miller, J.H, Yang, W. | | Deposit date: | 2004-08-24 | | Release date: | 2004-10-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair
Embo J., 23, 2004
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2A2K
 | | Crystal Structure of an active site mutant, C473S, of Cdc25B Phosphatase Catalytic Domain | | Descriptor: | CHLORIDE ION, M-phase inducer phosphatase 2, SULFATE ION | | Authors: | Sohn, J, Parks, J, Buhrman, G, Brown, P, Kristjansdottir, K, Safi, A, Yang, W, Edelsbrunner, H, Rudolph, J. | | Deposit date: | 2005-06-22 | | Release date: | 2006-01-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Experimental Validation of the Docking Orientation of Cdc25 with Its Cdk2-CycA Protein Substrate.
Biochemistry, 44, 2005
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1ZBI
 | | Bacillus halodurans RNase H catalytic domain mutant D132N in complex with 12-mer RNA/DNA hybrid | | Descriptor: | 5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3', 5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3', MAGNESIUM ION, ... | | Authors: | Nowotny, M, Gaidamakov, S.A, Crouch, R.J, Yang, W. | | Deposit date: | 2005-04-08 | | Release date: | 2005-07-12 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Cell(Cambridge,Mass.), 121, 2005
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1ZBF
 | | Crystal structure of B. halodurans RNase H catalytic domain mutant D132N | | Descriptor: | SULFATE ION, ribonuclease H-related protein | | Authors: | Nowotny, M, Gaidamakov, S.A, Crouch, R.J, Yang, W. | | Deposit date: | 2005-04-08 | | Release date: | 2005-07-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Cell(Cambridge,Mass.), 121, 2005
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2AOR
 | | Crystal structure of MutH-hemimethylated DNA complex | | Descriptor: | 5'-D(*CP*AP*GP*GP*(6MA)P*TP*CP*CP*AP*AP*GP*CP*TP*TP*GP*GP*AP*TP*CP*CP*TP*G)-3', CALCIUM ION, DNA mismatch repair protein mutH | | Authors: | Lee, J.Y, Chang, J, Joseph, N, Ghirlando, R, Rao, D.N, Yang, W. | | Deposit date: | 2005-08-13 | | Release date: | 2005-10-11 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage.
Mol.Cell, 20, 2005
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2IMW
 | | Mechanism of Template-Independent Nucleotide Incorporation Catalyzed by a Template-Dependent DNA Polymerase | | Descriptor: | 1,2-ETHANEDIOL, 2',3'-dideoxyadenosine triphosphate, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3', ... | | Authors: | Ling, H, Yang, W. | | Deposit date: | 2006-10-05 | | Release date: | 2007-01-16 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Mechanism of Template-independent Nucleotide Incorporation Catalyzed by a Template-dependent DNA Polymerase.
J.Mol.Biol., 365, 2007
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2G6K
 | | Structure of rat nNOS heme domain (BH4 bound) complexed with NO | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ARGININE, ... | | Authors: | Li, H, Igarashi, J, Jamal, J, Yang, W, Poulos, T.L. | | Deposit date: | 2006-02-24 | | Release date: | 2006-08-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
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2G6I
 | | Structure of rat nNOS heme domain (BH2-bound) in the reduced form | | Descriptor: | 7,8-DIHYDROBIOPTERIN, ACETATE ION, ARGININE, ... | | Authors: | Li, H, Igarashi, J, Jamal, J, Yang, W, Poulos, T.L. | | Deposit date: | 2006-02-24 | | Release date: | 2006-08-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
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2G6M
 | | Structure of rat nNOS heme domain (BH4 bound) complexed with CO | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ARGININE, ... | | Authors: | Li, H, Igarashi, J, Jamal, J, Yang, W, Poulos, T.L. | | Deposit date: | 2006-02-24 | | Release date: | 2006-08-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
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2G8F
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2G8U
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2G8K
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2G6H
 | | Structure of rat nNOS heme domain (BH4 bound) in the reduced form | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ARGININE, ... | | Authors: | Li, H, Igarashi, J, Jamal, J, Yang, W, Poulos, T.L. | | Deposit date: | 2006-02-24 | | Release date: | 2006-08-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
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2G8H
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2G6J
 | | Structure of rat nNOS (L337N) heme domain (4-aminobiopterin bound) complexed with NO | | Descriptor: | (1S,2S)-1-(2,4-DIAMINOPTERIDIN-6-YL)PROPANE-1,2-DIOL, ACETATE ION, ARGININE, ... | | Authors: | Li, H, Igarashi, J, Jamal, J, Yang, W, Poulos, T.L. | | Deposit date: | 2006-02-24 | | Release date: | 2006-08-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
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