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Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative
Descriptor:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE, COBALT (II) ION, ...
Authors:	Addlagatta, A, Hu, X, Liu, J.O, Matthews, B.W.
Deposit date:	2006-02-24
Release date:	2006-06-20
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Identification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases. Angew.Chem.Int.Ed.Engl., 45, 2006

2B7X

Sequential reorganization of beta-sheet topology by insertion of a single strand
Descriptor:	Lysozyme, SULFATE ION
Authors:	Sagermann, M, Matthews, B.W.
Deposit date:	2005-10-05
Release date:	2006-08-01
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Sequential reorganization of beta-sheet topology by insertion of a single strand. Protein Sci., 15, 2006

2GZ5

Human Type 1 methionine aminopeptidase in complex with ovalicin at 1.1 Ang
Descriptor:	3,4-DIHYDROXY-2-METHOXY-4-METHYL-3-[2-METHYL-3-(3-METHYL-BUT-2-ENYL) -OXIRANYL]-CYCLOHEXANONE, COBALT (II) ION, GLYCEROL, ...
Authors:	Addlagatta, A, Matthews, B.W.
Deposit date:	2006-05-10
Release date:	2006-05-23
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.1 Å)
Cite:	Structure of the angiogenesis inhibitor ovalicin bound to its noncognate target, human Type 1 methionine aminopeptidase. Protein Sci., 15, 2006

107L

STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1992-12-17
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structural basis of amino acid alpha helix propensity. Science, 260, 1993

108L

STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1992-12-17
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structural basis of amino acid alpha helix propensity. Science, 260, 1993

109L

STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1992-12-17
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Structural basis of amino acid alpha helix propensity. Science, 260, 1993

112L

STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1992-12-17
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structural basis of amino acid alpha helix propensity. Science, 260, 1993

110L

STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1992-12-17
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural basis of amino acid alpha helix propensity. Science, 260, 1993

111L

STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
Descriptor:	CHLORIDE ION, T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1992-12-17
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structural basis of amino acid alpha helix propensity. Science, 260, 1993

113L

STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1992-12-17
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structural basis of amino acid alpha helix propensity. Science, 260, 1993

115L

STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1992-12-17
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structural basis of amino acid alpha helix propensity. Science, 260, 1993

114L

STRUCTURAL BASIS OF ALPHA-HELIX PROPENSITY AT TWO SITES IN T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1992-12-17
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structural basis of amino acid alpha helix propensity. Science, 260, 1993

146L

ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Baldwin, E, Matthews, B.W.
Deposit date:	1993-10-15
Release date:	1994-01-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993

122L

THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1993-05-28
Release date:	1993-10-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993

184L

SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY
Descriptor:	2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, ISOBUTYLBENZENE, ...
Authors:	Morton, A, Matthews, B.W.
Deposit date:	1995-04-19
Release date:	1995-07-10
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity. Biochemistry, 34, 1995

137L

STRUCTURAL BASIS OF AMINO ACID ALPHA HELIX PROPENSITY
Descriptor:	T4 LYSOZYME
Authors:	Blaber, M, Matthews, B.W.
Deposit date:	1993-08-17
Release date:	1994-07-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Structural basis of amino acid alpha helix propensity. Science, 260, 1993

140L

ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Baldwin, E, Matthews, B.W.
Deposit date:	1993-10-15
Release date:	1994-01-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993

141L

ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Baldwin, E, Matthews, B.W.
Deposit date:	1993-10-15
Release date:	1994-01-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993

143L

ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Baldwin, E, Matthews, B.W.
Deposit date:	1993-10-15
Release date:	1994-01-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993

142L

ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Baldwin, E, Matthews, B.W.
Deposit date:	1993-10-15
Release date:	1994-01-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993

145L

ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:	Baldwin, E, Matthews, B.W.
Deposit date:	1993-10-15
Release date:	1994-01-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993

144L

ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:	Baldwin, E, Matthews, B.W.
Deposit date:	1993-10-15
Release date:	1994-01-31
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993

183L

SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY
Descriptor:	2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, INDENE, ...
Authors:	Morton, A, Matthews, B.W.
Deposit date:	1995-04-19
Release date:	1995-07-10
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity. Biochemistry, 34, 1995

185L

SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY
Descriptor:	2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, INDOLE, ...
Authors:	Morton, A, Matthews, B.W.
Deposit date:	1995-04-19
Release date:	1995-07-10
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity. Biochemistry, 34, 1995

187L

SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY
Descriptor:	2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PARA-XYLENE, ...
Authors:	Morton, A, Matthews, B.W.
Deposit date:	1995-04-19
Release date:	1995-07-10
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity. Biochemistry, 34, 1995

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