8Y1G
 
 | | The 1up conformation of the HKU1-B S protein in the apo state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | | Deposit date: | 2024-01-24 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.99 Å) | | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2.
Cell Res., 34, 2024
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8Y1A
 | | 1up-1 conformation of HKU1-B S protein after incubation of the receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | | Deposit date: | 2024-01-24 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2.
Cell Res., 34, 2024
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8Y1H
 | | The 2up formation of the HKU1-B S protein in the apo state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | | Deposit date: | 2024-01-24 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2.
Cell Res., 34, 2024
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8Y1B
 | | 1up-2 conformation of HKU1-B S protein after incubation of the receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | | Deposit date: | 2024-01-24 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2.
Cell Res., 34, 2024
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8Y19
 | | Closed conformation of HKU1-B S protein after incubation of the receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | | Deposit date: | 2024-01-24 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2.
Cell Res., 34, 2024
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8Y1C
 | | 2up-1 conformation of HKU1-B S protein after incubation of the receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | | Deposit date: | 2024-01-24 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2.
Cell Res., 34, 2024
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6K7V
 | | Structure of NLRP1 CARD filament | | Descriptor: | NACHT, LRR and PYD domains-containing protein 1 | | Authors: | Gong, Q, Xu, C, Zhang, J, Wu, B. | | Deposit date: | 2019-06-09 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.
Nat Commun, 12, 2021
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6NM3
 | | NMR structure of WW295 | | Descriptor: | WW295 peptide | | Authors: | Wang, G, Zarena, D. | | Deposit date: | 2019-01-10 | | Release date: | 2020-07-15 | | Last modified: | 2020-09-09 | | Method: | SOLUTION NMR | | Cite: | Two distinct amphipathic peptide antibiotics with systemic efficacy.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6NPI
 | | Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments | | Descriptor: | ({2-[(4-bromo-5-methyl-1,2-oxazol-3-yl)amino]-2-oxoethyl}sulfanyl)acetic acid, 2-pyrrol-1-ylbenzoic acid, Epstein-Barr nuclear antigen 1 | | Authors: | Messick, T.E. | | Deposit date: | 2019-01-17 | | Release date: | 2019-03-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.501 Å) | | Cite: | Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med, 11, 2019
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8Y1F
 | | The closed conformation of the HKU1-B S protein in the apo state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | | Deposit date: | 2024-01-24 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2.
Cell Res., 34, 2024
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8Y1E
 | | 3up-TM conformation of HKU1-B S protein after incubation of the receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | | Deposit date: | 2024-01-24 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2.
Cell Res., 34, 2024
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3VFA
 | | Crystal Structure of HIV-1 Protease Mutant V82A with novel P1'-Ligands GRL-02031 | | Descriptor: | (3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl [(1S,2R)-1-benzyl-2-hydroxy-3-([(4-methoxyphenyl)sulfonyl]{[(2R)-5-oxopyrrolidin-2-yl]methyl}amino)propyl]carbamate, CHLORIDE ION, SODIUM ION, ... | | Authors: | Yu, X.X, Wang, Y.F, Chang, Y.C.E, Weber, I.T. | | Deposit date: | 2012-01-09 | | Release date: | 2012-11-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring.
J.Med.Chem., 55, 2012
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3SGV
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6N51
 | | Metabotropic Glutamate Receptor 5 bound to L-quisqualate and Nb43 | | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... | | Authors: | Koehl, A, Hu, H, Feng, D, Sun, B, Weis, W.I, Skiniotis, G.S, Mathiesen, J.M, Kobilka, B.K. | | Deposit date: | 2018-11-20 | | Release date: | 2019-01-23 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural insights into the activation of metabotropic glutamate receptors.
Nature, 566, 2019
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3S34
 | | Structure of the 1121B Fab fragment | | Descriptor: | 1121B Fab heavy chain, 1121B Fab light chain, PHOSPHATE ION | | Authors: | Franklin, M.C. | | Deposit date: | 2011-05-17 | | Release date: | 2011-08-24 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
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3SGX
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6NPP
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6NWZ
 | | Crystal structure of Agd3 a novel carbohydrate deacetylase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | Authors: | Bamford, N.C, Howell, P.L. | | Deposit date: | 2019-02-07 | | Release date: | 2020-02-12 | | Last modified: | 2020-08-26 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation.
Nat Commun, 11, 2020
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3S29
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6NZE
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6NZP
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6NZR
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6NZH
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6K9F
 | | Structure of unknow protein 4 | | Descriptor: | Caspase recruitment domain-containing protein 8 | | Authors: | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | | Deposit date: | 2019-06-15 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.
Nat Commun, 12, 2021
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6NZQ
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