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5QUP
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BU of 5qup by Molmil
HumRadA1 soaked with 0.5 mM indazole in 10% DMSO
Descriptor: PHOSPHATE ION, RadA
Authors:Marsh, M, Hyvonen, M.
Deposit date:2020-01-27
Release date:2021-03-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Optimisation of crystal forms for structure-guided drug discovery
To be published
5QUJ
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BU of 5quj by Molmil
HumRadA1.2 soaked with napht-2,3-diol overnight 10 mM
Descriptor: PHOSPHATE ION, RadA, naphthalene-2,3-diol
Authors:Marsh, M, Hyvonen, M.
Deposit date:2020-01-27
Release date:2021-03-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Optimisation of crystal forms for structure-guided drug discovery
To be published
5QUK
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BU of 5quk by Molmil
Structure of unliganded HumRadA1.2
Descriptor: PHOSPHATE ION, RadA
Authors:Marsh, M, Hyvonen, M.
Deposit date:2020-01-27
Release date:2021-03-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Optimisation of crystal forms for structure-guided drug discovery
To be published
5QUN
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BU of 5qun by Molmil
Structure of unliganded HumRadA1.6
Descriptor: PHOSPHATE ION, RadA
Authors:Marsh, M, Hyvonen, M.
Deposit date:2020-01-27
Release date:2021-03-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Optimisation of crystal forms for structure-guided drug discovery
To be published
5QUM
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BU of 5qum by Molmil
Structure of unliganded HumRadA1.4
Descriptor: RadA
Authors:Marsh, M, Hyvonen, M.
Deposit date:2020-01-27
Release date:2021-03-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Optimisation of crystal forms for structure-guided drug discovery
To be published
5QUL
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BU of 5qul by Molmil
Structure of unliganded HumRadA1.3
Descriptor: PHOSPHATE ION, RadA
Authors:Marsh, M, Hyvonen, M.
Deposit date:2020-01-27
Release date:2021-03-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.278 Å)
Cite:Optimisation of crystal forms for structure-guided drug discovery
To be published
5QUT
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BU of 5qut by Molmil
HumRadA1 soaked with 10 mM indazole in 10% DMSO
Descriptor: 1H-indazole, PHOSPHATE ION, RadA
Authors:Marsh, M, Hyvonen, M.
Deposit date:2020-01-27
Release date:2021-03-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.248 Å)
Cite:Optimisation of crystal forms for structure-guided drug discovery
To be published
5QUS
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BU of 5qus by Molmil
HumRadA1 soaked with 5 mM indazole in 10% DMSO
Descriptor: 1H-indazole, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
Authors:Marsh, M, Hyvonen, M.
Deposit date:2020-01-27
Release date:2021-03-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.247 Å)
Cite:Optimisation of crystal forms for structure-guided drug discovery
To be published
5QUU
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BU of 5quu by Molmil
HumRadA1 as soaking control with 10% DMSO
Descriptor: DIMETHYL SULFOXIDE, PHOSPHATE ION, RadA
Authors:Marsh, M, Hyvonen, M.
Deposit date:2020-01-27
Release date:2021-03-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.248 Å)
Cite:Optimisation of crystal forms for structure-guided drug discovery
To be published
5QUR
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BU of 5qur by Molmil
HumRadA1 soaked with 2 mM indazole in 10% DMSO
Descriptor: 1H-indazole, PHOSPHATE ION, RadA
Authors:Marsh, M, Hyvonen, M.
Deposit date:2020-01-27
Release date:2021-03-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.247 Å)
Cite:Optimisation of crystal forms for structure-guided drug discovery
To be published
6WMI
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BU of 6wmi by Molmil
ZNF410 zinc fingers 1-5 with 17 mer blunt DNA Oligonucleotide
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*CP*AP*TP*CP*CP*CP*AP*TP*AP*AP*TP*AP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*TP*AP*TP*GP*GP*GP*AP*TP*GP*TP*G)-3'), ...
Authors:Ren, R, Horton, J.R, Cheng, X.
Deposit date:2020-04-21
Release date:2020-12-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
Mol.Cell, 81, 2021
6Y0K
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BU of 6y0k by Molmil
Sulfite oxidase from Thermus thermophilus with coordinated phosphate
Descriptor: (MOLYBDOPTERIN-S,S)-OXO-MOLYBDENUM, GLYCEROL, PHOSPHATE ION, ...
Authors:Djeghader, A, Soulimane, T.
Deposit date:2020-02-08
Release date:2020-08-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural evidence for a reaction intermediate mimic in the active site of a sulfite dehydrogenase.
Chem.Commun.(Camb.), 56, 2020
1RJW
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BU of 1rjw by Molmil
CRYSTAL STRUCTURE OF NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE FROM BACILLUS STEAROTHERMOPHILUS STRAIN LLD-R
Descriptor: Alcohol dehydrogenase, TRIFLUOROETHANOL, ZINC ION
Authors:Ceccarelli, C, Bahnson, B.J.
Deposit date:2003-11-20
Release date:2004-05-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure and Amide H/D Exchange of Binary Complexes of Alcohol Dehydrogenase from Bacillus stearothermophilus: Insight into Thermostability and Cofactor Binding
Biochemistry, 43, 2004
6TT2
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BU of 6tt2 by Molmil
The PH domain of Bruton's tyrosine kinase mutant R28C
Descriptor: MAGNESIUM ION, Tyrosine-protein kinase BTK, ZINC ION
Authors:Brear, P, Wagstaff, J, Hyvonen, M.
Deposit date:2019-12-23
Release date:2020-11-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C
To Be Published
7AYS
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BU of 7ays by Molmil
Structure of bovine trypsin determined from single femtosecond snapshots per orientation at room temperature
Descriptor: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
Authors:Jensen, M.
Deposit date:2020-11-13
Release date:2021-01-20
Last modified:2021-08-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High-resolution macromolecular crystallography at the FemtoMAX beamline with time-over-threshold photon detection.
J.Synchrotron Radiat., 28, 2021
6SIU
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BU of 6siu by Molmil
Crystal structure of IbpAFic2 covalently tethered to Cdc42
Descriptor: Cell division control protein 42 homolog, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Gulen, B, Roselin, M, Albers, M, Hedberg, C, Itzen, A, Pogenberg, V.
Deposit date:2019-08-12
Release date:2020-03-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture.
Nat.Chem., 12, 2020
5BQ0
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BU of 5bq0 by Molmil
Crystal structure of bruton agammaglobulinemia tyrosine kinase complexed with BMS-824171 AKA 6-[(3R)-3-(4-tert-bu tylbenzamido)piperidin-1-yl]-2-{[4-(morpholine-4-carbonyl) phenyl]amino}pyridine-3-carboxamide
Descriptor: 1,2-ETHANEDIOL, 4-(2-chlorophenyl)-7-[(4-methylpiperazin-1-yl)carbonyl]-9H-carbazole-1-carboxamide, DIMETHYL SULFOXIDE, ...
Authors:Muckelbauer, J.K.
Deposit date:2015-05-28
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton's tyrosine kinase (BTK) and Janus kinase 2 (JAK2).
Bioorg.Med.Chem.Lett., 25, 2015
5BPY
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BU of 5bpy by Molmil
Crystal structure of bruton agammaglobulinemia tyrosine kinase complexed with BMS-824171 AKA 6-[(3R)-3-(4-tert-bu tylbenzamido)piperidin-1-yl]-2-{[4-(morpholine-4-carbonyl) phenyl]amino}pyridine-3-carboxamide
Descriptor: 6-{(3R)-3-[(4-tert-butylbenzoyl)amino]piperidin-1-yl}-2-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}pyridine-3-carboxamide, Tyrosine-protein kinase BTK
Authors:Muckelbauer, J.K.
Deposit date:2015-05-28
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton's tyrosine kinase (BTK) and Janus kinase 2 (JAK2).
Bioorg.Med.Chem.Lett., 25, 2015
1JN7
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BU of 1jn7 by Molmil
Solution Structure of a CCHH mutant of the ninth CCHC Zinc Finger of U-shaped
Descriptor: U-shaped TRANSCRIPTIONAL COFACTOR, ZINC ION
Authors:Kowalski, K, Mackay, J.P.
Deposit date:2001-07-23
Release date:2002-09-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Characterization of the Conserved Interaction between GATA and FOG Family Proteins
J.Biol.Chem., 277, 2002
5KWQ
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BU of 5kwq by Molmil
Two Tandem RRM Domains of FBP-Interacting Repressor (FIR), also Known as PUF60
Descriptor: Poly(U)-binding-splicing factor PUF60
Authors:Crichlow, G.V, Yang, Y, Zhou, H, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-18
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5KW6
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BU of 5kw6 by Molmil
Two Tandem RRM Domains of PUF60 Bound to an AdML Pre-mRNA 3' Splice Site Analogue with a Modified Binding-Site Nucleic Acid Base
Descriptor: DNA (30-MER), Poly(U)-binding-splicing factor PUF60
Authors:Crichlow, G.V, Hsiao, H.-H, Albright, R, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-15
Release date:2017-08-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
2QFJ
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BU of 2qfj by Molmil
Crystal Structure of First Two RRM Domains of FIR Bound to ssDNA from a Portion of FUSE
Descriptor: DNA (5'-D(*DTP*DCP*DGP*DGP*DGP*DAP*DTP*DTP*DTP*DTP*DTP*DTP*DAP*DTP*DTP*DTP*DTP*DGP*DTP*DGP*DTP*DTP*DAP*DTP*DT)-3'), FBP-interacting repressor
Authors:Crichlow, G.V, Yang, Y, Fan, C, Lolis, E, Braddock, D.
Deposit date:2007-06-27
Release date:2008-03-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition
EMBO J., 27, 2007
2MPL
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BU of 2mpl by Molmil
Solution structure of the PR domain of FOG-1
Descriptor: Zinc finger protein ZFPM1
Authors:Mackay, J.P, Clifton, M.K, Westman, B.J, Blobel, G.A.
Deposit date:2014-05-26
Release date:2014-10-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins.
Plos One, 9, 2014
2HLS
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BU of 2hls by Molmil
The crystal structure of a protein disulfide oxidoreductase from Aeropyrum pernix k1
Descriptor: CHLORIDE ION, protein disulfide oxidoreductase
Authors:D'Ambrosio, K, De Simone, G.
Deposit date:2006-07-10
Release date:2006-10-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Novel Member of the Protein Disulfide Oxidoreductase Family from Aeropyrum pernix K1: Structure, Function and Electrostatics.
J.Mol.Biol., 362, 2006
1JKW
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BU of 1jkw by Molmil
STRUCTURE OF CYCLIN MCS2
Descriptor: CYCLIN H
Authors:Andersen, G, Poterszman, A, Moras, D, Thierry, J.C.
Deposit date:1996-10-11
Release date:1997-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of human cyclin H.
FEBS Lett., 397, 1996

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