5WEO
Activated GluA2 complex bound to glutamate, cyclothiazide, and STZ in digitonin
Summary for 5WEO
| Entry DOI | 10.2210/pdb5weo/pdb |
| EMDB information | 8819 8820 8821 8822 8823 |
| Descriptor | Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit chimera, GLUTAMIC ACID, CYCLOTHIAZIDE (3 entities in total) |
| Functional Keywords | ion channel, transport protein |
| Biological source | Rattus norvegicus (Rat) More |
| Total number of polymer chains | 4 |
| Total formula weight | 464155.90 |
| Authors | Twomey, E.C.,Yelshanskaya, M.V.,Grassucci, R.A.,Frank, J.,Sobolevsky, A.I. (deposition date: 2017-07-10, release date: 2017-08-02, Last modification date: 2019-11-20) |
| Primary citation | Twomey, E.C.,Yelshanskaya, M.V.,Grassucci, R.A.,Frank, J.,Sobolevsky, A.I. Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature, 549:60-65, 2017 Cited by PubMed: 28737760DOI: 10.1038/nature23479 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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