5LCW
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution
Summary for 5LCW
| Entry DOI | 10.2210/pdb5lcw/pdb |
| EMDB information | 4037 |
| Descriptor | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 13, ... (18 entities in total) |
| Functional Keywords | complex, ubiquitin, e3 ligase, ubiquitin ligase, cullin, ring, cell cycle, mitosis, spindle checkpoint, degron |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 23 |
| Total formula weight | 1331085.90 |
| Authors | Alfieri, C.,Chang, L.,Zhang, Z.,Yang, J.,Maslen, S.,Skehel, M.,Barford, D. (deposition date: 2016-06-22, release date: 2016-08-10, Last modification date: 2019-10-23) |
| Primary citation | Alfieri, C.,Chang, L.,Zhang, Z.,Yang, J.,Maslen, S.,Skehel, M.,Barford, D. Molecular basis of APC/C regulation by the spindle assembly checkpoint. Nature, 536:431-436, 2016 Cited by PubMed: 27509861DOI: 10.1038/nature19083 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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