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4XXB

Crystal structure of human MDM2-RPL11

Summary for 4XXB
Entry DOI10.2210/pdb4xxb/pdb
Descriptor60S ribosomal protein L11, E3 ubiquitin-protein ligase Mdm2, IMIDAZOLE, ... (6 entities in total)
Functional Keywordsmdm2, rpl11, modpipe model of up, rna binding protein-metal binding protein complex, rna binding protein/metal binding protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight37417.54
Authors
Zheng, J.,Chen, Z. (deposition date: 2015-01-30, release date: 2015-08-12, Last modification date: 2023-11-08)
Primary citationZheng, J.,Lang, Y.,Zhang, Q.,Cui, D.,Sun, H.,Jiang, L.,Chen, Z.,Zhang, R.,Gao, Y.,Tian, W.,Wu, W.,Tang, J.,Chen, Z.
Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation
Genes Dev., 29:1524-1534, 2015
Cited by
PubMed: 26220995
DOI: 10.1101/gad.261792.115
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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