3VIE

HIV-gp41 fusion inhibitor Sifuvirtide

Summary for 3VIE

Entry DOI	10.2210/pdb3vie/pdb
Descriptor	Envelope glycoprotein gp160, Sifuvirtide (3 entities in total)
Functional Keywords	6-helix bundle, membrane fusion inhibition, hiv, viral protein-antiviral protein complex, viral protein/antiviral protein
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	6
Total formula weight	26609.59
Authors	Yao, X.,Waltersperger, S.,Wang, M.T.,Cui, S. (deposition date: 2011-09-29, release date: 2012-01-18, Last modification date: 2023-11-08)
Primary citation	Yao, X.,Chong, H.,Zhang, C.,Waltersperger, S.,Wang, M.,Cui, S.,He, Y. Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor sifuvirtide J.Biol.Chem., 287:6788-6796, 2012 Cited by PubMed: 22228771 DOI: 10.1074/jbc.M111.317883 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation