2R6P
Fit of E protein and Fab 1A1D-2 into 24 angstrom resolution cryoEM map of Fab complexed with dengue 2 virus.
Summary for 2R6P
| Entry DOI | 10.2210/pdb2r6p/pdb |
| EMDB information | 1418 |
| Descriptor | Major envelope protein E, Heavy chain of 1A1D-2, Light chain of 1A1D-2 (3 entities in total) |
| Functional Keywords | fab, dengue, virus, neutralization, virus-immune system complex, icosahedral virus, virus/immune system |
| Biological source | Dengue virus 2 Puerto Rico/PR159-S1/1969 More |
| Total number of polymer chains | 7 |
| Total formula weight | 221965.94 |
| Authors | Lok, S.M.,Kostyuchenko, V.K.,Holdaway, H.A.,Chipman, P.R.,Kuhn, R.J.,Rossmann, M.G. (deposition date: 2007-09-06, release date: 2007-12-25, Last modification date: 2024-02-21) |
| Primary citation | Lok, S.M.,Kostyuchenko, V.,Nybakken, G.E.,Holdaway, H.A.,Battisti, A.J.,Sukupolvi-Petty, S.,Sedlak, D.,Fremont, D.H.,Chipman, P.R.,Roehrig, J.T.,Diamond, M.S.,Kuhn, R.J.,Rossmann, M.G. Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Nat.Struct.Mol.Biol., 15:312-317, 2008 Cited by PubMed: 18264114DOI: 10.1038/nsmb.1382 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (24 Å) |
Structure validation
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