2M59
Spatial structure of dimeric VEGFR2 membrane domain in DPC micelles
Summary for 2M59
Entry DOI | 10.2210/pdb2m59/pdb |
NMR Information | BMRB: 19041 |
Descriptor | Vascular endothelial growth factor receptor 2 (1 entity in total) |
Functional Keywords | vegfr2, receptor tyrosine kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cell junction . Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted . Isoform 3: Secreted: P35968 |
Total number of polymer chains | 2 |
Total formula weight | 8262.13 |
Authors | Mineev, K.S.,Arseniev, A.S.,Shulepko, M.A.,Lyukmanova, E.N. (deposition date: 2013-02-19, release date: 2014-03-12, Last modification date: 2024-05-15) |
Primary citation | Manni, S.,Mineev, K.S.,Usmanova, D.,Lyukmanova, E.N.,Shulepko, M.A.,Kirpichnikov, M.P.,Winter, J.,Matkovic, M.,Deupi, X.,Arseniev, A.S.,Ballmer-Hofer, K. Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation. Structure, 22:1077-1089, 2014 Cited by PubMed: 24980797DOI: 10.1016/j.str.2014.05.010 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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