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1TUP

TUMOR SUPPRESSOR P53 COMPLEXED WITH DNA

Summary for 1TUP
Entry DOI10.2210/pdb1tup/pdb
DescriptorDNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR ), ... (5 entities in total)
Functional Keywordsantigen p53, antitumor protein-dna complex, antitumor protein/dna
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
Total number of polymer chains5
Total formula weight86840.24
Authors
Cho, Y.,Gorina, S.,Jeffrey, P.D.,Pavletich, N.P. (deposition date: 1995-07-11, release date: 1995-07-11, Last modification date: 2024-02-14)
Primary citationCho, Y.,Gorina, S.,Jeffrey, P.D.,Pavletich, N.P.
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science, 265:346-355, 1994
Cited by
PubMed: 8023157
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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