1RF8
Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490
Summary for 1RF8
| Entry DOI | 10.2210/pdb1rf8/pdb |
| Related | 1AP8 |
| Descriptor | Eukaryotic translation initiation factor 4E, Eukaryotic initiation factor 4F subunit p150, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, ... (4 entities in total) |
| Functional Keywords | initiation factor, protein biosynthesis, translation regulation, biosynthetic protein, translation |
| Biological source | Saccharomyces cerevisiae (baker's yeast) More |
| Cellular location | Cytoplasm: P39935 |
| Total number of polymer chains | 2 |
| Total formula weight | 36814.36 |
| Authors | Gross, J.D.,Moerke, N.J.,von der Haar, T.,Lugovskoy, A.A.,Sachs, A.B.,McCarthy, J.E.G.,Wagner, G. (deposition date: 2003-11-07, release date: 2003-12-23, Last modification date: 2024-03-06) |
| Primary citation | Gross, J.D.,Moerke, N.J.,von der Haar, T.,Lugovskoy, A.A.,Sachs, A.B.,McCarthy, J.E.,Wagner, G. Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. Cell(Cambridge,Mass.), 115:739-750, 2003 Cited by PubMed: 14675538DOI: 10.1016/S0092-8674(03)00975-9 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
Download full validation report
