1RF8
Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Eukaryotic translation initiation factor 4E | polymer | 213 | 24211.2 | 1 | UniProt (P07260) Pfam (PF01652) In PDB | Saccharomyces cerevisiae (baker's yeast) | eIF4E, eIF-4E, mRNA cap-binding protein, eIF-4F 25 kDa subunit |
| 2 | B | Eukaryotic initiation factor 4F subunit p150 | polymer | 100 | 11087.4 | 1 | UniProt (P39935) Pfam (PF12152) In PDB | Saccharomyces cerevisiae (baker's yeast) | eIF4F p150, eIF-4F p150, mRNA cap-binding protein complex subunit p150 |
| 3 | A | S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | non-polymer | 264.4 | 4 | Chemie (MTN) | |||
| 4 | A | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE | non-polymer | 458.2 | 1 | Chemie (M7G) |
Sequence modifications
A: 1 - 213 (UniProt: P07260)
B: 215 - 314 (UniProt: P39935)
| PDB | External Database | Details |
|---|---|---|
| Cys 120 | Arg 120 | conflict |
| Cys 132 | Arg 132 | conflict |
| Cys 169 | Ser 169 | conflict |
| Cys 200 | Ser 200 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 215 | - | cloning artifact |
| Ser 216 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35298.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1515.8 | |
| All* | Total formula weight | 36814.4 |
