1NW9
STRUCTURE OF CASPASE-9 IN AN INHIBITORY COMPLEX WITH XIAP-BIR3
Summary for 1NW9
Entry DOI | 10.2210/pdb1nw9/pdb |
Descriptor | Baculoviral IAP repeat-containing protein 4, caspase 9, apoptosis-related cysteine protease, ZINC ION (3 entities in total) |
Functional Keywords | caspase-9, xiap, caspase inhibition, caspase activation, dimerization, apoptosis |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 41866.65 |
Authors | Shiozaki, E.N.,Chai, J.,Rigotti, D.J.,Riedl, S.J.,Li, P.,Srinivasula, S.M.,Alnemri, E.S.,Fairman, R.,Shi, Y. (deposition date: 2003-02-05, release date: 2003-03-25, Last modification date: 2024-02-14) |
Primary citation | Shiozaki, E.N.,Chai, J.,Rigotti, D.J.,Riedl, S.J.,Li, P.,Srinivasula, S.M.,Alnemri, E.S.,Fairman, R.,Shi, Y. Mechanism of XIAP-Mediated Inhibition of Caspase-9 Mol.Cell, 11:519-527, 2003 Cited by PubMed: 12620238DOI: 10.1016/S1097-2765(03)00054-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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