1AQU

ESTROGEN SULFOTRANSFERASE WITH BOUND INACTIVE COFACTOR PAP AND 17-BETA ESTRADIOL

Summary for 1AQU

Entry DOI	10.2210/pdb1aqu/pdb
Descriptor	ESTROGEN SULFOTRANSFERASE, ADENOSINE-3'-5'-DIPHOSPHATE, ESTRADIOL, ... (4 entities in total)
Functional Keywords	transferase, pap, sulfotransferase, sulfonation, estrogen, 17-beta estradiol, steroid-binding
Biological source	Mus musculus (house mouse)
Cellular location	Cytoplasm: P49891
Total number of polymer chains	2
Total formula weight	72967.85
Authors	Kakuta, Y.,Negishi, M.,Pedersen, L.C. (deposition date: 1997-08-01, release date: 1998-10-28, Last modification date: 2024-05-22)
Primary citation	Kakuta, Y.,Pedersen, L.G.,Carter, C.W.,Negishi, M.,Pedersen, L.C. Crystal structure of estrogen sulphotransferase. Nat.Struct.Biol., 4:904-908, 1997 Cited by PubMed Abstract: The structure of estrogen sulphotransferase has been solved in the presence of inactive cofactor PAP and substrate 17 beta-estradiol. This structure reveals structural similarities between cytosolic sulphotransferases and nucleotide kinases. PubMed: 9360604 DOI: 10.1038/nsb1197-904 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation