9ZZV

Human T-cell receptor (TCR) with computationally designed orthogonal interface

Summary for 9ZZV

• Entry DOI: 10.2210/pdb9zzv/pdb
• Descriptor: Orthogonal T-cell receptor alpha constant domain (combiC26a), Orthogonal T-cell receptor beta constant domain (combiC26b) (3 entities in total)
• Functional Keywords: tcr, computational protein design, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 26821.75

Authors

Kinjo, T.,Yu, S.,Nicely, N.I.,Leaver-Fay, A.,Kim, W.Y.,Kuhlman, B. (deposition date: 2026-01-08, release date: 2026-01-28)

• Primary citation: Kinjo, T.,Yu, S.,Nicely, N.I.,Leaver-Fay, A.,Kim, W.Y.,Kuhlman, B.; Computational design of orthogonal TCR alpha beta interfaces for dual TCR therapeutics; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)