9ZYE

Crystal structure of HTLV-1 protease bound to UMass6 at 2.7 angstroms with truncated flaps

Summary for 9ZYE

• Entry DOI: 10.2210/pdb9zye/pdb
• Descriptor: HTLV-1 Protease, TETRAETHYLENE GLYCOL, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-ethylbutyl)amino}-1-benzyl-2-hydroxypropyl]carbamate, ... (4 entities in total)
• Functional Keywords: htlv-1, protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, viral protein, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Human T-cell leukemia virus type I
• Total number of polymer chains: 2
• Total formula weight: 25903.10

Authors

Shaqra, A.M.,Lockbaum, G.J.,Intravaia, L.E.,Schiffer, C.A. (deposition date: 2026-01-05, release date: 2026-01-21)

• Primary citation: Shaqra, A.M.,Lockbaum, G.J.,Intravaia, L.E.,Schiffer, C.A.; Crystal structure of HTLV-1 protease bound to UMass6 at 2.7 angstroms with truncated flaps; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)