9ZWS

Crystal structure of the N4BP2 polynucleotide kinase domain complexed with ATP or ADP, Mg, and the trinucleotide substrate ACA or its 5'-phosphorylated product pACA.

Summary for 9ZWS

• Entry DOI: 10.2210/pdb9zws/pdb
• Descriptor: NEDD4-binding protein 2, 5'-OH RNA (5'-r(ApCpA)-3') or 5'-phosphorylated RNA (5'-r(pApCpA)-3'), MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: transferase; polynucleotide kinase; catalysis; enzyme reaction; catalytic mechanism; phosphoryl transfer, rna, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 68423.61

Authors

Wang, H.,Stanley, R.E. (deposition date: 2026-01-03, release date: 2026-09-23)

• Primary citation: Wang, H.,Stanley, R.E.; Structure, Specificity, and Catalytic Mechanism of the Polynucleotide Kinase Domains from the Human N4BP2 Kinase Family; Nat Commun, 2026

Experimental method

X-RAY DIFFRACTION (2 Å)