9ZWE

Soluble ectodomain of Herpes simplex virus 2 (HSV-2) glycoprotein B (gB) in the prefusion conformation in complex with 2c and D48 Fabs

Summary for 9ZWE

• Entry DOI: 10.2210/pdb9zwe/pdb
• EMDB information: 74907
• Descriptor: Envelope glycoprotein B, Antibody D48 Heavy Chain, Antibody D48 Light Chain, ... (5 entities in total)
• Functional Keywords: prefusion, ectodomain, viral fusion protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human herpesvirus 2 strain HG52; More
• Total number of polymer chains: 15
• Total formula weight: 539113.88

Authors

Sponholtz, M.R.,Johnson, N.V.,McLellan, J.S. (deposition date: 2026-01-01, release date: 2026-02-04)

• Primary citation: Sponholtz, M.R.,Ma, D.,Byrne, P.O.,Shu, Y.,Warren, C.,Thambi, N.,McCool, R.S.,Slein, M.D.,Johnson, N.V.,Rose, W.A.,Zhang, L.,Durr, E.,Wang, D.,McLellan, J.M.; Structure-based design of soluble prefusion-stabilized herpes simplex virus type 2 glycoprotein B antigens; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.75 Å)