9ZQV

Crystal structure of wild-type Bruton's Tyrosine Kinase (BTK) in the apo form

Summary for 9ZQV

• Entry DOI: 10.2210/pdb9zqv/pdb
• Descriptor: Tyrosine-protein kinase BTK, 1,2-ETHANEDIOL, IODIDE ION, ... (5 entities in total)
• Functional Keywords: nonreceptor protein tyrosine kinase, b-cell activation, btk, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 31955.51

Authors

Gajewski, S. (deposition date: 2025-12-19, release date: 2026-07-15)

• Primary citation: Sievers, Q.; Molecular and Structural Basis of Pan-Resistance to BTK Degraders and Inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)