9ZOU

OXA-23-JDB/PQ-1-219, 40 min complex

This is a non-PDB format compatible entry.

Summary for 9ZOU

• Entry DOI: 10.2210/pdb9zou/pdb
• Descriptor: Beta-lactamase OXA-23, (2S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S)-2,3-dihydroazet-3-yl]sulfanyl}-2-methyl-2H-pyrrole-5-carboxylic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: antibiotic resistance, beta-lactamase, inhibitor, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Acinetobacter baumannii
• Total number of polymer chains: 1
• Total formula weight: 31560.49

Authors

Smith, C.A.,Maggiolo, A.M.,Vakulenko, S.B.,Toth, M. (deposition date: 2025-12-16, release date: 2026-01-14)

• Primary citation: Toth, M.,Stewart, N.K.,Maggiolo, A.M.,Quan, P.,Khan, M.M.K.,Cox, J.,Castro Cabello, M.,Buynak, J.D.,Smith, C.A.,Vakulenko, S.B.; Potent Inhibition of OXA-23 and Unimpeded Access to PBPs Underpins the Broad Activity of the Novel Carbapenem JDB/PQ-1-219 Against Class D Carbapenemases; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)