9ZOB

CryoEM structure of DNA-PK bound to N7 nucleosome, state 2

Summary for 9ZOB

• Entry DOI: 10.2210/pdb9zob/pdb
• EMDB information: 74481
• Descriptor: DNA-dependent protein kinase catalytic subunit, DNA (154-MER), Unknown peptide, ... (10 entities in total)
• Functional Keywords: nhej, dna-pk, ku70/80, dna repair, nucleosome, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 14
• Total formula weight: 812708.61

Authors

Lu, W.,He, Y. (deposition date: 2025-12-15, release date: 2026-09-16)

• Primary citation: Lu, W.,Vogt, A.,Lees-Miller, S.P.,He, Y.; DNA-PK driven nucleosome unwrapping enables NHEJ in chromatin; Nat Commun, 2026; DOI: 10.1038/s41467-026-77534-9

Experimental method

ELECTRON MICROSCOPY (3.8 Å)