9ZO3

X-ray structure of SARS-CoV-2 main protease covalently bound to inhibitor GRL-062-22 at 1.65 A

This is a non-PDB format compatible entry.

Summary for 9ZO3

• Entry DOI: 10.2210/pdb9zo3/pdb
• Descriptor: 3C-like proteinase nsp5, (3S)-N-{(1S,2S)-1-(1,3-benzothiazol-2-yl)-1-hydroxy-3-[(3S)-2-oxopiperidin-3-yl]propan-2-yl}-2-[3-methyl-N-(trifluoroacetyl)-L-valyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, SODIUM ION, ... (4 entities in total)
• Functional Keywords: sars-cov-2, main protease, 3clpro, csbid, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34522.28

Authors

Mesecar, A.D.,Lendy, E.K.,Jayashankar, U.,Bogan, S.N.,Ghosh, A.K. (deposition date: 2025-12-15, release date: 2025-12-24)

• Primary citation: Mesecar, A.D.,Lendy, E.K.,Jayashankar, U.,Bogan, S.N.,Ghosh, A.K.; X-ray structure of SARS-CoV-2 main protease covalently bound to inhibitor GRL-062-22 at 1.65 A; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)