9ZNC

CryoEM structure of the DNA-PK complex bound to N20 nucleosome

Summary for 9ZNC

• Entry DOI: 10.2210/pdb9znc/pdb
• EMDB information: 74444
• Descriptor: Histone H3, DNA repair protein Ku80, Histone H4, ... (10 entities in total)
• Functional Keywords: nhej, dna-pk, dna repair, nucleosome, ku70/80, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 14
• Total formula weight: 818889.51

Authors

Lu, W.,He, Y. (deposition date: 2025-12-12, release date: 2026-09-16)

• Primary citation: Lu, W.,Vogt, A.,Lees-Miller, S.P.,He, Y.; DNA-PK driven nucleosome unwrapping enables NHEJ in chromatin; Nat Commun, 2026; DOI: 10.1038/s41467-026-77534-9

Experimental method

ELECTRON MICROSCOPY (3.93 Å)