9ZF4

The structure of human Vacuolar Protein Sorting 34 catalytic domain bound to RD-II-83

This is a non-PDB format compatible entry.

Summary for 9ZF4

• Entry DOI: 10.2210/pdb9zf4/pdb
• Related: 9DKP 9E4V 9NIN 9ORM
• Descriptor: Phosphatidylinositol 3-kinase catalytic subunit type 3, methyl 2-[(8R)-pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-benzothiazole-6-carboxylate, GLYCEROL, ... (9 entities in total)
• Functional Keywords: phosphatidylinositol 3-phosphate, lipid regulator, autophagy, membrane trafficking, endocytosis, enzyme, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 69319.64

Authors

Litchfield, C.M.,Abiodun, W.O.,Peterson, M.A.,Moody, J.D. (deposition date: 2025-12-01, release date: 2026-04-22)

• Primary citation: Litchfield, C.M.,Abiodun, W.O.,Burtch, M.,Cartwright, J.,Dass, R.,Singleton, J.D.,Doukov, T.,Peterson, M.A.,Moody, J.D.; The structure of human Vacuolar Protein Sorting 34 catalytic domain bound to RD-II-83; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.09 Å)