9ZCN

Avian TRPM8 (Parus major) fully-swapped, closed, ligand-free in the presence of calcium, structure resolved in cell vesicles

Summary for 9ZCN

• Entry DOI: 10.2210/pdb9zcn/pdb
• EMDB information: 74036
• Descriptor: Transient receptor potential cation channel subfamily M member 8 (1 entity in total)
• Functional Keywords: trpm8, transient receptor potential melastatin 8, membrane protein, parus major
• Biological source: Parus major (Great Tit)
• Total number of polymer chains: 4
• Total formula weight: 508868.06

Authors

Choi, K.Y.,Lin, X.,Cheng, Y.,Julius, D. (deposition date: 2025-11-24, release date: 2026-03-25)

• Primary citation: Choi, K.Y.,Lin, X.,Cheng, Y.,Julius, D.; Structural energetics of cold sensitivity; Nature, 2026; DOI: 10.1038/s41586-026-10276-2

Experimental method

ELECTRON MICROSCOPY (3.5 Å)