9Z7E

Crystal structure of Vps29 in complex with C. thermophilum Gyp6L (87 to 107)

Summary for 9Z7E

• Entry DOI: 10.2210/pdb9z7e/pdb
• Related: 9Z7D
• Descriptor: Isoform 2 of Vacuolar protein sorting-associated protein 29, GTPase-activating protein GYP6 like protein (3 entities in total)
• Functional Keywords: retromer, endosome, membrane trafficking, protein transport, tbc domain, gap, gtpase activation.
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 23340.67

Authors

Chen, K.-E.,Collins, B. (deposition date: 2025-11-17, release date: 2026-10-28)

• Primary citation: Alves, A.C.,Chen, K.E.,Mayer, L.M.,Guo, Q.,Stephens, E.J.,Liu, M.,Healy, M.D.,Collins, B.M.,Mayer, A.; The GTPase activating protein Gyp6 binds Retromer and inactivates Rab7/Ypt7 to coordinate the formation of endosomal carriers; Biorxiv, 2026; DOI: 10.64898/2026.01.23.701266

Experimental method

X-RAY DIFFRACTION (2.13 Å)