9Z7B

Cryo-EM structure of Protein involved in colonization (Pic) from Enteroaggregative Escherichia coli complexed with the fragment antigen binding domain of monoclonal antibody 40

This is a non-PDB format compatible entry.

Summary for 9Z7B

• Entry DOI: 10.2210/pdb9z7b/pdb
• EMDB information: 73874
• Descriptor: Serine protease pic autotransporter, Heavy chain of the fragment antigen binding domain of monoclonal antibody 40, Light chain of the fragment antigen binding domain of monoclonal antibody 40 (3 entities in total)
• Functional Keywords: protease, beta-helix, secreted, monoclonal antibody, hydrolase, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Escherichia coli 042; More
• Total number of polymer chains: 3
• Total formula weight: 157187.99

Authors

Buckley, D.P.,Berndsen, Z.T. (deposition date: 2025-11-16, release date: 2026-06-03)

• Primary citation: Buckley, D.P.,Akhtar, M.,Thapa, M.,Schmitz, A.,Turner, J.,Vickers, T.J.,Khatoon, N.,Kaisar, H.,Coggin, J.A.,Ganguli, D.,Sheikh, A.,Laird, R.M.,Poly, F.,Porter, C.K.,Ruiz-Perez, F.,Miller, M.J.,Bhuiyan, T.R.,Qadri, F.,Trillo-Muyo, S.,Dolan, B.,van der Post, S.,Ellebedy, A.,Berndsen, Z.T.,Fleckenstein, J.M.; Human infection with enterotoxigenic E. coli elicits antibodies that broadly neutralize mucin-degrading proteases of pathogenic E. coli and Shigella; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.69 Å)