9Z78

Cryo-EM structure of Enterotoxigenic Escherichia coli autotransporter A (EatA) complexed with the fragment antigen binding domain of monoclonal antibody 15

This is a non-PDB format compatible entry.

Summary for 9Z78

• Entry DOI: 10.2210/pdb9z78/pdb
• EMDB information: 73871
• Descriptor: Serine protease EatA, Heavy chain of the fragment antigen binding domain of monoclonal antibody 15, Light chain of the fragment antigen binding domain of monoclonal antibody 15 (3 entities in total)
• Functional Keywords: protease, beta-helix, secreted, monoclonal antibody, hydrolase, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Escherichia coli; More
• Total number of polymer chains: 3
• Total formula weight: 158377.29

Authors

Buckley, D.P.,Berndsen, Z.T. (deposition date: 2025-11-16, release date: 2026-06-03)

• Primary citation: Buckley, D.P.,Akhtar, M.,Thapa, M.,Schmitz, A.,Turner, J.,Vickers, T.J.,Khatoon, N.,Kaisar, H.,Coggin, J.A.,Ganguli, D.,Sheikh, A.,Laird, R.M.,Poly, F.,Porter, C.K.,Ruiz-Perez, F.,Miller, M.J.,Bhuiyan, T.R.,Qadri, F.,Trillo-Muyo, S.,Dolan, B.,van der Post, S.,Ellebedy, A.,Berndsen, Z.T.,Fleckenstein, J.M.; Human infection with enterotoxigenic E. coli elicits antibodies that broadly neutralize mucin-degrading proteases of pathogenic E. coli and Shigella; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.64 Å)