9Z77
Cryo-EM structure of Enterotoxigenic Escherichia coli autotransporter A (EatA) complexed with the fragment antigen binding domain of monoclonal antibody G12
Summary for 9Z77
| Entry DOI | 10.2210/pdb9z77/pdb |
| EMDB information | 73870 |
| Descriptor | Serine protease EatA, Heavy chain of the fragment antigen binding domain of monoclonal antibody G12, Light chain of the fragment antigen binding domain of monoclonal antibody G12 (3 entities in total) |
| Functional Keywords | protease, beta-helix, secreted, monoclonal antibody, hydrolase, hydrolase-immune system complex, hydrolase/immune system |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 3 |
| Total formula weight | 159012.66 |
| Authors | |
| Primary citation | Buckley, D.P.,Akhtar, M.,Thapa, M.,Schmitz, A.,Turner, J.,Vickers, T.J.,Khatoon, N.,Kaisar, H.,Coggin, J.A.,Ganguli, D.,Sheikh, A.,Laird, R.M.,Poly, F.,Porter, C.K.,Ruiz-Perez, F.,Miller, M.J.,Bhuiyan, T.R.,Qadri, F.,Trillo-Muyo, S.,Dolan, B.,van der Post, S.,Ellebedy, A.,Berndsen, Z.T.,Fleckenstein, J.M. Human infection with enterotoxigenic E. coli elicits antibodies that broadly neutralize mucin-degrading proteases of pathogenic E. coli and Shigella To Be Published, |
| Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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