9Z5S

Cryo-EM of the sarco(endo)plasmic reticulum calcium ATPase (SERCA) in presence of calcium and CDN1163

Summary for 9Z5S

• Entry DOI: 10.2210/pdb9z5s/pdb
• EMDB information: 73823
• Descriptor: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, N-(2-methylquinolin-8-yl)-4-[(propan-2-yl)oxy]benzamide, O-DODECANYL OCTAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: atpase, calcium, eukaryotic, hydrolase
• Biological source: Oryctolagus cuniculus (rabbit)
• Total number of polymer chains: 2
• Total formula weight: 221083.75

Authors

Nguyen, V.H.,Primeau, J.O.,Cruz-Cortes, C.,Lemieux, M.J.,Espinoza-Fonseca, L.M.,Young, H.S. (deposition date: 2025-11-12, release date: 2026-11-04)

• Primary citation: Nguyen, V.H.,Primeau, J.O.,Cruz-Cortes, C.,Lemieux, M.J.,Espinoza-Fonseca, M.,Young, H.S.; Cryo-EM reveals a transmembrane allosteric site and activation mechanism for the SERCA calcium pump; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.5 Å)