9Z4O

Cryo-EM structure of human Wntless in its apo state

Summary for 9Z4O

• Entry DOI: 10.2210/pdb9z4o/pdb
• EMDB information: 73810
• Descriptor: Protein wntless homolog (1 entity in total)
• Functional Keywords: wnt transporter, wnt secretion, wnt signaling, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 66088.14

Authors

Ge, Y.,de Almeida Magalhaes, T.,Wu, H.,Yadav, G.P.,Wang, Z.,Salic, A.,Jiang, J.,Huang, P. (deposition date: 2025-11-10, release date: 2026-06-10)

• Primary citation: Ge, Y.,de Almeida Magalhaes, T.,Wu, H.,van den Boomen, D.J.H.,Nguyen, T.U.,Dou, T.,Yadav, G.P.,Lee, S.,Wang, Z.,Lemoff, A.,Luo, X.,Jin, Z.,Jiang, J.,Salic, A.,Huang, P.; Conformational cycling of the Wntless transporter drives trafficking and secretion of Wnt morphogens; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.63 Å)