9Z3B

Structure C-terminal human Mesothelin Peptide bound to MSLNB703 Fab

Summary for 9Z3B

Entry DOI	10.2210/pdb9z3b/pdb
Descriptor	MSLNB703 Light Chain, MSLNB703 Heavy Chain, Mesothelin, ... (4 entities in total)
Functional Keywords	mesothelin antibody, antitumor protein-immune system complex, antitumor protein/immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	12
Total formula weight	204302.26
Authors	Shaffer, P.L.,Ember, S. (deposition date: 2025-11-06, release date: 2026-01-21)
Primary citation	Smans, K.,Shaffer, P.,Ember, S.,Gavine, P. JNJ-79032421, a Novel Membrane-restricted Mesothelin-targeting T-cell-engaging Bispecific Antibody for the Treatment of Mesothelin-positive Cancers To Be Published,
Experimental method	X-RAY DIFFRACTION (1.96 Å)

Structure validation