9Z21

Cryo-EM structure of human TRPM4 channel in complex with calcium and NC1 at 37 degrees Celsius (consensus)

This is a non-PDB format compatible entry.

Summary for 9Z21

• Entry DOI: 10.2210/pdb9z21/pdb
• EMDB information: 73759
• Descriptor: Transient receptor potential cation channel subfamily M member 4, CALCIUM ION, Necrocide 1 (3 entities in total)
• Functional Keywords: ion channel, trp channel, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 539608.42

Authors

Hu, J.,Lu, W.,Du, J. (deposition date: 2025-11-04, release date: 2026-06-10)

• Primary citation: Jinhong, H.,Sofia, I.,Sung Jin, P.,Junuk, L.,Jennifer, C.,Garrett, O.,Jiangnan, S.,Juan, D.,Wei, L.; Temperature and intrinsic Ca2+ reshape TRPM4 pharmacology; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.83 Å)